CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.238 | Recoverin; domain 1 |
|
1.10.238.110 | Diacylglycerol kinase alpha. |
Domain Context
CATH Clusters
| Superfamily | Diacylglycerol kinase alpha. |
| Functional Family | Diacylglycerol kinase |
Enzyme Information
| 2.7.1.107 |
Diacylglycerol kinase (ATP).
based on mapping to UniProt P23743
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
-!- Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. -!- Activity is stimulated by certain phospholipids. -!- In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. -!- cf. EC 2.7.1.174.
|
UniProtKB Entries (1)
| P23743 |
DGKA_HUMAN
Homo sapiens
Diacylglycerol kinase alpha
|
PDB Structure
| PDB | 1TUZ |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
NMR structure of Diacylglycerol kinase alpha, NESGC target HR532
To be Published
|