CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.50.90
Functional Family Thermonuclease

Enzyme Information

3.1.31.1
Micrococcal nuclease.
based on mapping to UniProt P00644
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.
-!- Hydrolyzes double- or single-stranded substrate. -!- Similar enzymes: Chlamydomonas nuclease, spleen phosphodiesterase, spleen endonuclease. -!- Formerly EC 3.1.4.7.

UniProtKB Entries (1)

P00644
NUC_STAAU
Staphylococcus aureus
Thermonuclease

PDB Structure

PDB 1STH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray crystal structures of staphylococcal nuclease complexed with the competitive inhibitor cobalt(II) and nucleotide.
Loll, P.J., Quirk, S., Lattman, E.E., Garavito, R.M.
Biochemistry