CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.110 | 4 Propeller |
|
2.110.10 | Hemopexin |
|
2.110.10.10 | Hemopexin-like domain |
Domain Context
CATH Clusters
| Superfamily | Hemopexin-like domain |
| Functional Family | 72 kDa type IV collagenase |
Enzyme Information
| 3.4.24.24 |
Gelatinase A.
based on mapping to UniProt P08253
Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.
-!- Belongs to peptidase family M10B.
|
UniProtKB Entries (1)
| P08253 |
MMP2_HUMAN
Homo sapiens
72 kDa type IV collagenase
|
PDB Structure
| PDB | 1RTG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The C-terminal (haemopexin-like) domain structure of human gelatinase A (MMP2): structural implications for its function.
FEBS Lett.
|