CATH Classification

Domain Context

CATH Clusters

Superfamily Ricin (A Subunit), domain 2
Functional Family

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt P81446
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

P81446
ML1_VISAL
Viscum album
Beta-galactoside-specific lectin 1

PDB Structure

PDB 1PUU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mistletoe lectin I in complex with galactose and lactose reveals distinct sugar-binding properties
Mikeska, R., Wacker, R., Arni, R., Singh, T.P., Mikhailov, A., Gabdoulkhakov, A., Voelter, W., Betzel, C.
Acta Crystallogr.,Sect.F