CATH Classification

Domain Context

CATH Clusters

Superfamily Single-stranded right-handed beta-helix, Pectin lyase-like
Functional Family Endopolygalacturonase D

Enzyme Information

3.2.1.15
Endo-polygalacturonase.
based on mapping to UniProt P26213
(1,4-alpha-D-galacturonosyl)(n+m) + H(2)O = (1,4-alpha-D- galacturonosyl)(n) + (1,4-alpha-D-galacturonosyl)(m).
-!- The enzyme catalyzes the random hydrolysis of (1->4)-alpha-D- galactosiduronic linkages in pectate and other galacturonans. -!- Different forms of the enzyme have different tolerances to methyl esterification of the substrate.

UniProtKB Entries (1)

P26213
PGLR1_ASPNG
Aspergillus niger
Endopolygalacturonase I

PDB Structure

PDB 1NHC
External Links
Method X-RAY DIFFRACTION
Organism Aspergillus
Primary Citation
Structural insights into the processivity of endopolygalacturonase I from Aspergillus niger.
van Pouderoyen, G., Snijder, H.J., Benen, J.A., Dijkstra, B.W.
Febs Lett.