CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8X225
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q8X225
DIM5_NEUCR
Neurospora crassa OR74A
Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5

PDB Structure

PDB 1ML9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase
Zhang, X., Tamaru, H., Khan, S.I., Horton, J.R., Keefe, L.J., Selker, E.U., Cheng, X.
Cell(Cambridge,Mass.)