CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.470.10
Functional Family Branched-chain-amino-acid aminotransferase

Enzyme Information

2.6.1.42
Branched-chain-amino-acid transaminase.
based on mapping to UniProt P0AB80
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

UniProtKB Entries (1)

P0AB80
ILVE_ECOLI
Escherichia coli K-12
Branched-chain-amino-acid aminotransferase

PDB Structure

PDB 1I1M
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
Okada, K., Hirotsu, K., Hayashi, H., Kagamiyama, H.
Biochemistry