CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.12
Alpha-lytic endopeptidase.
based on mapping to UniProt P00778
Preferential cleavage: Ala-|-Xaa, Val-|-Xaa in bacterial cell walls, elastin and other proteins.
-!- Belongs to peptidase family S1E.

UniProtKB Entries (1)

P00778
PRLA_LYSEN
Lysobacter enzymogenes
Alpha-lytic protease

PDB Structure

PDB 1GBI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
Mace, J.E., Agard, D.A.
J.Mol.Biol.