CATH Classification

Domain Context

CATH Clusters

Superfamily 1.50.10.10
Functional Family alpha-1,2-Mannosidase

Enzyme Information

3.2.1.113
Mannosyl-oligosaccharide 1,2-alpha-mannosidase.
based on mapping to UniProt P32906
Hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
-!- Involved in the synthesis of glycoproteins.

UniProtKB Entries (1)

P32906
MNS1_YEAST
Saccharomyces cerevisiae S288C
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

PDB Structure

PDB 1G6I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and function of Class I a1,2-mannosidases involved in glycoprotein biosynthesis.
Herscovics, A., Lipari, F., Sleno, B., Romera, P.A., Vallee, F., Yip, P., Howell, P.A.
CARBOHYDRATE BIOENGINEERING. INTERDISCIPLINARY APPROACHES.