1 keywords

CATH Domain 1b9lH00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1130 GTP Cyclohydrolase I, domain 2
Homologous Superfamily 3.30.1130.10 GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain

Domain Context

CATH Clusters

Superfamily 3.30.1130.10
Functional Family D-erythro-7,8-dihydroneopterin triphosphate epimerase

Enzyme Information

5.1.99.7
Dihydroneopterin triphosphate 2'-epimerase.
based on mapping to UniProt P0AC19
7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin 3'-triphosphate.
-!- The enzyme, found in gammaproteobacteria, has almost no activity with 7,8-dihydroneopterin.

UniProtKB Entries (1)

P0AC19
FOLX_ECOLI
Escherichia coli K-12
Dihydroneopterin triphosphate 2'-epimerase

PDB Structure

PDB 1B9L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of 7,8-dihydroneopterin triphosphate epimerase.
Ploom, T., Haussmann, C., Hof, P., Steinbacher, S., Bacher, A., Richardson, J., Huber, R.
Structure Fold.Des.