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CATH Superfamily 4.10.520.10

IHF-like DNA-binding proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
IHF-like DNA-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4099: DNA-binding protein HU alpha

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NADH:ubiquinone reductase (H(+)-translocating). [EC: 1.6.5.3]
NADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out).
  • The complex is present in mitochondria and aerobic bacteria.
  • Breakdown of the complex can release EC 1.6.99.3.
  • In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD(+) to NADH.
 3 A0A0X8R403 A0A1E4JQN9 U2WUQ7
TRNA pseudouridine(38-40) synthase. [EC: 5.4.99.12]
tRNA uridine(38-40) = tRNA pseudouridine(38-40).
  • The uridylate residues at positions 38, 39 and 40 of nearly all tRNAs are isomerized to pseudouridine.
  • TruA specifically modifies uridines at positions 38, 39, and/or 40 in the anticodon stem loop of tRNAs with highly divergent sequences and structures.
 1 D5BP86
Phosphoribosylformylglycinamidine synthase. [EC: 6.3.5.3]
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine + L-glutamate.
    		 1 U2EN38