# STOCKHOLM 1.0
#=GF ID 3.60.15.10/FF/19806
#=GF DE Hypothetical bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase + cyclase/dehydrase
#=GF AC 3.60.15.10/FF/19806
#=GF TP FunFam
#=GF DR CATH: 4.2
#=GF DR DOPS: 8.808
#=GS O86346/331-434_469-580      AC O86346
#=GS O86346/331-434_469-580      OS Mycobacterium tuberculosis H37Rv
#=GS O86346/331-434_469-580      DE 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
#=GS O86346/331-434_469-580      DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS O86346/331-434_469-580      DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS O86346/331-434_469-580      DR GO; GO:0005829; GO:0005886; 
#=GS O86346/331-434_469-580      DR EC; 4.3.2.3; 
#=GS A0A083WGR6/331-434_469-580  AC A0A083WGR6
#=GS A0A083WGR6/331-434_469-580  OS Mycobacterium bovis
#=GS A0A083WGR6/331-434_469-580  DE Bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase
#=GS A0A083WGR6/331-434_469-580  DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS A0A083WGR6/331-434_469-580  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium bovis; 
#=GS A0A083WGR6/331-434_469-580  DR EC; 4.3.2.3; 
#=GS A0A0H3P7V0/331-434_469-580  AC A0A0H3P7V0
#=GS A0A0H3P7V0/331-434_469-580  OS Mycobacterium bovis AF2122/97
#=GS A0A0H3P7V0/331-434_469-580  DE POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE) + CYCLASE/DEHYDRASE
#=GS A0A0H3P7V0/331-434_469-580  DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS A0A0H3P7V0/331-434_469-580  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium bovis; 
#=GS A0A0H3P7V0/331-434_469-580  DR EC; 4.3.2.3; 
#=GS L7N575/331-434_469-580      AC L7N575
#=GS L7N575/331-434_469-580      OS Mycobacterium tuberculosis CDC1551
#=GS L7N575/331-434_469-580      DE Fumarylacetoacetate hydrolase family/metallo-beta-lactamase superfamily protein
#=GS L7N575/331-434_469-580      DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS L7N575/331-434_469-580      DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS L7N575/331-434_469-580      DR EC; 4.3.2.3; 
#=GS A5U0X9/331-434_469-580      AC A5U0X9
#=GS A5U0X9/331-434_469-580      OS Mycobacterium tuberculosis H37Ra
#=GS A5U0X9/331-434_469-580      DE Fumarylacetoacetate hydrolase family/metallo-beta-lactamase superfamily protein
#=GS A5U0X9/331-434_469-580      DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS A5U0X9/331-434_469-580      DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS A5U0X9/331-434_469-580      DR EC; 4.3.2.3; 
#=GS A0A045INM4/331-434_469-580  AC A0A045INM4
#=GS A0A045INM4/331-434_469-580  OS Mycobacterium tuberculosis
#=GS A0A045INM4/331-434_469-580  DE 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
#=GS A0A045INM4/331-434_469-580  DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS A0A045INM4/331-434_469-580  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS A0A045INM4/331-434_469-580  DR EC; 4.3.2.3; 
#=GS M8DJI0/331-434_469-580      AC M8DJI0
#=GS M8DJI0/331-434_469-580      OS Mycobacterium orygis 112400015
#=GS M8DJI0/331-434_469-580      DE Bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase
#=GS M8DJI0/331-434_469-580      DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS M8DJI0/331-434_469-580      DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium orygis; 
#=GS M8DJI0/331-434_469-580      DR EC; 4.3.2.3; 
#=GS A0A109SLL4/331-434_469-580  AC A0A109SLL4
#=GS A0A109SLL4/331-434_469-580  OS Mycobacterium microti
#=GS A0A109SLL4/331-434_469-580  DE Bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase
#=GS A0A109SLL4/331-434_469-580  DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS A0A109SLL4/331-434_469-580  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium microti; 
#=GS A0A109SLL4/331-434_469-580  DR EC; 4.3.2.3; 
#=GS A0A0H3M955/331-434_469-580  AC A0A0H3M955
#=GS A0A0H3M955/331-434_469-580  OS Mycobacterium bovis BCG str. Pasteur 1173P2
#=GS A0A0H3M955/331-434_469-580  DE Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase + cyclase/dehydrase
#=GS A0A0H3M955/331-434_469-580  DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS A0A0H3M955/331-434_469-580  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium bovis; 
#=GS A0A0H3M955/331-434_469-580  DR EC; 4.3.2.3; 
#=GS A0A0G4DUY3/331-434_469-580  AC A0A0G4DUY3
#=GS A0A0G4DUY3/331-434_469-580  OS Mycobacterium caprae
#=GS A0A0G4DUY3/331-434_469-580  DE Fumarylacetoacetate hydrolase family/metallo-beta-lactamase superfamily protein (Possible bifunctional enzym e: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isom erase) + cyclase/dehydrase)
#=GS A0A0G4DUY3/331-434_469-580  DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS A0A0G4DUY3/331-434_469-580  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium caprae; 
#=GS A0A0G4DUY3/331-434_469-580  DR EC; 4.3.2.3; 
#=GS A0A0H3L781/331-434_469-580  AC A0A0H3L781
#=GS A0A0H3L781/331-434_469-580  OS Mycobacterium tuberculosis str. Erdman = ATCC 35801
#=GS A0A0H3L781/331-434_469-580  DE Bifunctional2-hydroxyhepta-2,4-diene-1,7-dioateisomerase/cyclase/dehydrase
#=GS A0A0H3L781/331-434_469-580  DR GENE3D; 64861e502b2590f183997515ea75ed5c/331-434_469-580; 
#=GS A0A0H3L781/331-434_469-580  DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS A0A0H3L781/331-434_469-580  DR EC; 4.3.2.3; 
#=GS A0A109SUX6/332-578          AC A0A109SUX6
#=GS A0A109SUX6/332-578          OS Mycobacterium africanum
#=GS A0A109SUX6/332-578          DE Bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/cyclase/dehydrase
#=GS A0A109SUX6/332-578          DR GENE3D; 30715e9b0cc207fc1265825ef599d888/332-578; 
#=GS A0A109SUX6/332-578          DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium africanum; 
#=GS F8M4I4/332-578              AC F8M4I4
#=GS F8M4I4/332-578              OS Mycobacterium africanum GM041182
#=GS F8M4I4/332-578              DE Putative bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase
#=GS F8M4I4/332-578              DR GENE3D; 30715e9b0cc207fc1265825ef599d888/332-578; 
#=GS F8M4I4/332-578              DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium africanum; 
#=GF TC 232.7 5.7E-73
#=GF SQ 13
O86346/331-434_469-580              PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A0A083WGR6/331-434_469-580          PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A0A0H3P7V0/331-434_469-580          PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
L7N575/331-434_469-580              PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A5U0X9/331-434_469-580              PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A0A045INM4/331-434_469-580          PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
M8DJI0/331-434_469-580              PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A0A109SLL4/331-434_469-580          PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A0A0H3M955/331-434_469-580          PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A0A0G4DUY3/331-434_469-580          PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A0A0H3L781/331-434_469-580          PFTRGLHEVADRVWAWTLPDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGP----------------------------------LRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAEAA
A0A109SUX6/332-578                  -FTRGLHEVADRVWAWTLPVGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAE--
F8M4I4/332-578                      -FTRGLHEVADRVWAWTLPVGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDALITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLGPVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAHTTADSVVHVADAGVLFAGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVTGPDGIRAVRGYLAHIAEQAE--
#=GC scorecons                      2999999999999999999499999999999999999999999999999999999999999999999999999999999999999999999999999999999911111111111111111111111111111111119999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999922
#=GC scorecons_70                   _******************_************************************************************************************__________________________________**************************************************************************************************************__
#=GC scorecons_80                   _******************_************************************************************************************__________________________________**************************************************************************************************************__
#=GC scorecons_90                   _******************_************************************************************************************__________________________________**************************************************************************************************************__
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