The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36582: Pyruvate decarboxylase isozyme 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pyruvate decarboxylase activity GO:0004737
Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.
4 P06169 (/IDA) P16467 (/IDA) P26263 (/IDA) Q6FJA3 (/IDA)
Carboxy-lyase activity GO:0016831
Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.
3 Q59MU3 (/ISS) Q60A74 (/ISS) Q81QE0 (/ISS)
Pyruvate decarboxylase activity GO:0004737
Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.
2 C8VE96 (/RCA) P87208 (/RCA)
Branched-chain-2-oxoacid decarboxylase activity GO:0047433
Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2).
2 P06169 (/IMP) P16467 (/IMP)
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
1 Q07471 (/IPI)
Pyruvate decarboxylase activity GO:0004737
Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.
1 P16467 (/IGI)
Pyruvate decarboxylase activity GO:0004737
Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.
1 P26263 (/IMP)
Pyruvate decarboxylase activity GO:0004737
Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.
1 Q09737 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q07471 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P33287 (/IPI)
Branched-chain-2-oxoacid decarboxylase activity GO:0047433
Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2).
1 Q6QBS4 (/IDA)
Phenylpyruvate decarboxylase activity GO:0050177
Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.
1 P87208 (/RCA)

There are 25 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aromatic amino acid family catabolic process to alcohol via Ehrlich pathway GO:0000949
The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
3 P06169 (/IGI) P16467 (/IGI) P26263 (/IGI)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
3 P06169 (/IDA) P16467 (/IDA) Q6FJA3 (/IDA)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
3 O42873 (/NAS) Q92345 (/NAS) Q9P7P6 (/NAS)
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
3 O42873 (/NAS) Q92345 (/NAS) Q9P7P6 (/NAS)
L-phenylalanine catabolic process GO:0006559
The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.
3 P06169 (/IGI) P16467 (/IGI) P26263 (/IGI)
Tryptophan catabolic process GO:0006569
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
3 P06169 (/IGI) P16467 (/IGI) P26263 (/IGI)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
2 C8VE96 (/RCA) P87208 (/RCA)
Glycolytic fermentation to ethanol GO:0019655
The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.
2 P06169 (/IDA) P16467 (/IDA)
Aromatic amino acid family catabolic process to alcohol via Ehrlich pathway GO:0000949
The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
1 Q59MU3 (/ISS)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 Q9FFT4 (/IEP)
Ethanol metabolic process GO:0006067
The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
1 P26263 (/IMP)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
1 P16467 (/IGI)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
1 Q09737 (/ISO)
Branched-chain amino acid biosynthetic process GO:0009082
The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
1 Q6QBS4 (/IDA)
Isoleucine biosynthetic process GO:0009097
The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
1 O06335 (/ISS)
Valine biosynthetic process GO:0009099
The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.
1 O06335 (/ISS)
Indoleacetic acid biosynthetic process GO:0009684
The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants.
1 Q81QE0 (/ISS)
Glycolytic fermentation to ethanol GO:0019655
The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.
1 P16467 (/IGI)
Glycolytic fermentation to ethanol GO:0019655
The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.
1 Q09737 (/ISO)
Response to anoxia GO:0034059
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
1 O82647 (/IMP)
Penicillin biosynthetic process GO:0042318
The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
1 P87208 (/RCA)
Ethanol biosynthetic process involved in glucose fermentation to ethanol GO:0043458
The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, as part of the process of glucose catabolism to ethanol, CO2 and ATP.
1 Q4WXX9 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q07471 (/IMP)
Positive regulation of thiamine biosynthetic process GO:0090180
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
1 Q07471 (/IMP)
Positive regulation of thiamine biosynthetic process GO:0090180
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
1 Q07471 (/IPI)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 O42873 (/IDA) O82647 (/IDA) P06169 (/IDA) Q09737 (/IDA) Q6FJA3 (/IDA) Q9FFT4 (/IDA) Q9P7P6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 O42873 (/IDA) P06169 (/IDA) P16467 (/IDA) Q07471 (/IDA) Q09737 (/IDA) Q9P7P6 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P83779 (/IDA) P9WG37 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 G8BHF2 (/IDA) P83779 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 P87208 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 O82647 (/IDA)
Yeast-form cell wall GO:0030445
The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.
1 P83779 (/IDA)
Hyphal cell wall GO:0030446
The cell wall surrounding a fungal hypha.
1 P83779 (/IDA)
Biofilm matrix GO:0097311
A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.
1 P83779 (/IDA)