The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 26884: Pyruvate dehydrogenase (Cytochrome)

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Pyruvate dehydrogenase (quinone). [EC: 1.2.5.1]
Pyruvate + ubiquinone + H(2)O = acetate + CO(2) + ubiquinol.
  • This bacterial enzyme is located on the inner surface of the cytoplasmic membrane and coupled to the respiratory chain via ubiquinone.
  • Does not accept menaquinone.
  • Activity is greatly enhanced by lipids.
  • Requires thiamine diphosphate.
  • The enzyme can also form acetoin.
13 A0A077JYZ4 A0A0A8RGG0 A0A0C7AQ45 A0A0E1B710 A0A0F6RW01 A0A0H2ZKR5 A0A0P1DI65 A0A157YZT0 A0A1D5BSR8 A0A1E9C123
(3 more...)