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CATH Superfamily 3.40.50.970

Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25432: Putative acetolactate synthase large subunit

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Acetolactate synthase. [EC: 2.2.1.6]
2 pyruvate = 2-acetolactate + CO(2).
  • The reaction shown is in the pathway of biosynthesis of valine.
  • The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine.
  • Formerly EC 4.1.3.18.
 22 A0A089SB96 A0A0E8VIK8 A0A0G4DW04 A0A0H3LFY1 A0A0H3MI61 A0A0H3P5Z8 A0A0T9ZGE4 A0A0U0RE80 A0A0U0RFI8 A0A0U0RJ53
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