The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Class I glutamine amidotransferase (GATase) domain

This superfamily represents the class I glutamine amidotransferase domain. Glutamine amidotransferase (GATase) enzymes catalyse the removal of the ammonia group from glutamine and then transfer this group to a substrate to form a new carbon-nitrogen group PMID:4355768. The GATase domain exists either as a separate polypeptidic subunit or as part of a larger polypeptide fused in different ways to a synthase domain. Two classes of GATase domains have been identified PMID:3298209,PMID:6086650: class-I (also known as trpG-type or triad) and class-II (also known as purF-type or Ntn). This entry also include the DJ-1/PfpI protein that contains a catalytic triad or dyad different from the class I GAT triad.

PMID:4355768 PMID:3298209 PMID:6086650 (INTERPRO:IPR029062)

GO Diversity

Unique GO annotations
443 Unique GO terms

EC Diversity

Unique EC annotations
162 Unique EC terms

Species Diversity

Unique species annotations
20774 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 815
Domain clusters (>95% seq id): 99
Domain clusters (>35% seq id): 60
Unique PDBs: 285
Structural Clusters (5A): 12
Structural Clusters (9A): 7
FunFam Clusters: 92
Unique EC: 162
Unique GO: 443
Unique Species: 20774