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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 57730: Thiazole biosynthesis adenylyltransferase ThiF

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sulfur carrier protein ThiS adenylyltransferase. [EC: 2.7.7.73]
ATP + [ThiS] = diphosphate + adenylyl-[ThiS].
  • The enzyme catalyzes the adenylation of ThiS, a sulfur carrier protein involved in the biosynthesis of thiamine.
  • The enzyme shows significant structural similarity to ubiquitin- activating enzyme.
  • In Escherichia coli, but not in Bacillus subtilis, the enzyme forms a cross link from Cys-184 to the ThiS carboxy terminus (the position that is also thiolated) via an acyldisulfide.
  • Formerly EC 2.7.7.n3.
 312 A0A017I6B1 A0A017I6B1 A0A023Z5U8 A0A023Z5U8 A0A024L9Q8 A0A024L9Q8 A0A025BMA6 A0A025BMA6 A0A026RKF0 A0A026RKF0
(302 more...)