The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 292115: Acyl-CoA synthetase (NDP forming)
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fatty-acyl-CoA synthase activity GO:0004321
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.
|
3 | Q5LKJ3 (/ISS) Q5LKU2 (/ISS) Q5LPZ9 (/ISS) |
|
Acetate-CoA ligase activity GO:0003987
Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
|
1 | Q8IL89 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P76594 (/IPI) |
|
Peptidyl-lysine acetyltransferase activity GO:0052858
Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.
|
1 | P76594 (/IMP) |
|
Peptide-lysine-N-acetyltransferase activity GO:0061733
Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.
|
1 | P76594 (/IDA) |
|
Peptide-lysine-N-acetyltransferase activity GO:0061733
Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.
|
1 | P76594 (/IMP) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
3 | Q5LKJ3 (/ISS) Q5LKU2 (/ISS) Q5LPZ9 (/ISS) |
|
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
|
1 | Q8IL89 (/ISS) |
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
1 | Q8IL89 (/ISS) |
|
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | P76594 (/IMP) |
|
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | P76594 (/IMP) |
|
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
|
1 | P76594 (/IDA) |
|
Internal peptidyl-lysine acetylation GO:0018393
The addition of an acetyl group to a non-terminal lysine residue in a protein.
|
1 | P76594 (/IMP) |
|
Regulation of protein homooligomerization GO:0032462
Any process that modulates the frequency, rate or extent of protein homooligomerization.
|
1 | P76594 (/IDA) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
1 | P76594 (/IDA) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.