The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 291944: Methionine adenosyltransferase 2 subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Methionine adenosyltransferase regulator activity GO:0048270
Modulates the activity of methionine adenosyltransferase.
8 Q29RI9 (/ISS) Q4QQZ4 (/ISS) Q54VU3 (/ISS) Q566L8 (/ISS) Q5BJJ6 (/ISS) Q5R4E0 (/ISS) Q5U2R0 (/ISS) Q99LB6 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9NZL9 (/IPI)
Oxidoreductase activity, acting on CH-OH group of donors GO:0016614
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
1 Q74AV3 (/ISS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q9NZL9 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q99LB6 (/ISO)
Methionine adenosyltransferase regulator activity GO:0048270
Modulates the activity of methionine adenosyltransferase.
1 Q9NZL9 (/IDA)
Methionine adenosyltransferase regulator activity GO:0048270
Modulates the activity of methionine adenosyltransferase.
1 Q99LB6 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
8 Q29RI9 (/ISS) Q4QQZ4 (/ISS) Q54VU3 (/ISS) Q566L8 (/ISS) Q5BJJ6 (/ISS) Q5R4E0 (/ISS) Q5U2R0 (/ISS) Q99LB6 (/ISS)
Polysaccharide biosynthetic process GO:0000271
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
1 Q74AV3 (/ISS)
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 Q9NZL9 (/IDA)
S-adenosylmethionine biosynthetic process GO:0006556
The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 Q99LB6 (/ISO)
Methylation GO:0032259
The process in which a methyl group is covalently attached to a molecule.
1 Q9NZL9 (/TAS)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Methionine adenosyltransferase complex GO:0048269
A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.
8 Q29RI9 (/ISS) Q4QQZ4 (/ISS) Q54VU3 (/ISS) Q566L8 (/ISS) Q5BJJ6 (/ISS) Q5R4E0 (/ISS) Q5U2R0 (/ISS) Q99LB6 (/ISS)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 Q9NZL9 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9NZL9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q99LB6 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q99LB6 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9NZL9 (/TAS)
Methionine adenosyltransferase complex GO:0048269
A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.
1 Q9NZL9 (/IDA)
Methionine adenosyltransferase complex GO:0048269
A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.
1 Q99LB6 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q9NZL9 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q99LB6 (/ISO)