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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 291028: Rhamnulose-1-phosphate aldolase/alcohol dehydrogen...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sorbitol-6-phosphate 2-dehydrogenase. [EC: 1.1.1.140]
D-sorbitol 6-phosphate + NAD(+) = D-fructose 6-phosphate + NADH.
    		 571 A0A011NE29 A0A017I807 A0A023V374 A0A023Z1Q4 A0A024KPM2 A0A025CX69 A0A026RUL9 A0A026V8Q4 A0A027U7M3 A0A028A6I7
    (561 more...)
    Rhamnulose-1-phosphate aldolase. [EC: 4.1.2.19]
    L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.
      		 12 A0A080UF32 A0A0G8F3A4 A0A0H3E5I2 A0A0M0KV04 A0A150L1K5 A0A167UH56 A0A1D3QJX4 A0A1G4LFC4 B7HWT3 B9IRD9
      (2 more...)
      Alcohol dehydrogenase. [EC: 1.1.1.1]
      (1) An alcohol + NAD(+) = an aldehyde or ketone + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
      • Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.
      • The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
      		 10 A0A0F5RHH2 A0A0M0KV04 A0A1C4EX28 A0A1G4LFC4 A0A1J9U5Z0 A0A1M8YBK0 B7HWT3 B9IRD9 C2S5M0 G4P004
      Lactaldehyde dehydrogenase. [EC: 1.2.1.22]
      (S)-lactaldehyde + NAD(+) + H(2)O = (S)-lactate + NADH.
        		 5 A0A0G8F3A4 A0A0M0KV04 A0A150L1K5 A0A1G4LFC4 G4P004