The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 290528: Polyketide synthase peptide synthetase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-aminoadipate-semialdehyde dehydrogenase activity GO:0004043
Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.
3 A0A1D8PCV7 (/IDA) P07702 (/IDA) P40976 (/IDA)
L-aminoadipate-semialdehyde dehydrogenase activity GO:0004043
Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.
3 A0A1D8PCV7 (/IMP) P07702 (/IMP) P40976 (/IMP)
L-aminoadipate-semialdehyde dehydrogenase activity GO:0004043
Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.
1 A0A1D8PCV7 (/IGI)
L-aminoadipate-semialdehyde dehydrogenase activity GO:0004043
Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.
1 Q5B1H0 (/RCA)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Secondary metabolic process GO:0019748
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
33 A2QBI9 (/NAS) A2QBQ2 (/NAS) A2QDU0 (/NAS) A2QG45 (/NAS) A2QH58 (/NAS) A2QH90 (/NAS) A2QHV2 (/NAS) A2QIQ8 (/NAS) A2QR54 (/NAS) A2QT17 (/NAS)
(23 more)
Lysine biosynthetic process via aminoadipic acid GO:0019878
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.
3 A0A1D8PCV7 (/IMP) P07702 (/IMP) P40976 (/IMP)
Secondary metabolite biosynthetic process GO:0044550
The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
3 Q4WAZ9 (/IMP) Q5AZ36 (/IMP) Q5BG07 (/IMP)
Lysine biosynthetic process GO:0009085
The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.
2 A0A1D8PCV7 (/IMP) P40976 (/IMP)
Lysine metabolic process GO:0006553
The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid.
1 Q5B1H0 (/RCA)
Lysine biosynthetic process GO:0009085
The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.
1 P40976 (/IDA)
Nonribosomal peptide biosynthetic process GO:0019184
The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
1 Q4WAZ9 (/ISM)
Secondary metabolic process GO:0019748
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
1 A5ABG0 (/IGC)
Lysine biosynthetic process via aminoadipic acid GO:0019878
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.
1 P07702 (/IDA)
Lysine biosynthetic process via aminoadipic acid GO:0019878
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.
1 A0A1D8PCV7 (/IGI)
Secondary metabolite biosynthetic process GO:0044550
The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
1 Q5BG07 (/IEP)
Secondary metabolite biosynthetic process GO:0044550
The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
1 Q5BG07 (/IGC)
Pseurotin A biosynthetic process GO:1900790
The chemical reactions and pathways resulting in the formation of pseurotin A.
1 Q4WAZ9 (/IMP)
Negative regulation of lysine biosynthetic process via aminoadipic acid GO:1902987
Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.
1 P40976 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P40976 (/IDA) Q10896 (/IDA) Q50631 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q10896 (/IDA) Q50631 (/IDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
1 Q10896 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P40976 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P07702 (/NAS)