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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 290287: NAD(P) transhydrogenase subunit alpha

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NAD(P)(+) transhydrogenase (Re/Si-specific). [EC: 1.6.1.2]
NADPH + NAD(+) = NADP(+) + NADH.
  • The enzyme from heart mitochondria is Re-specific with respect to NAD(+) and Si-specific with respect to NADP(+) (cf. EC 1.6.1.1.).
 5182 A0A011MH23 A0A011MH23 A0A011N064 A0A011N064 A0A011NSF7 A0A011NSF7 A0A011PTL2 A0A011PTL2 A0A011Q170 A0A011Q170
(5172 more...)
NAD(P)(+) transhydrogenase (Si-specific). [EC: 1.6.1.1]
NADPH + NAD(+) = NADP(+) + NADH.
  • Si-specific with respect to both NAD(+) and NADP(+).
  • Also acts with deamino coenzymes.
 172 A0A024UZ99 A0A024UZ99 A0A024VZN6 A0A024VZN6 A0A069B463 A0A069B463 A0A0D5HL83 A0A0D5HL83 A0A0E1SCV2 A0A0E1SCV2
(162 more...)
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase. [EC: 2.3.1.129]
(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetyl-alpha-D- glucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)- N-acetyl-alpha-D-glucosamine.
  • Involved with EC 2.4.1.182 and EC 2.7.1.130 in the biosynthesis of the phosphorylated glycolipid, lipid A, in the outer membrane of Escherichia coli.
 8 A0A0F3QP97 A0A0F3QP97 H8LMZ5 H8LMZ5 Q7PA73 Q7PA73 Q92FZ3 Q92FZ3
Alanine dehydrogenase. [EC: 1.4.1.1]
L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH.
    		 4 A0A0Y0EE61 A0A0Y0EE61 E1X7J5 E1X7J5
    Aspartate transaminase. [EC: 2.6.1.1]
    L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
    • Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.
    • This activity can be formed from EC 2.6.1.57 by controlled proteolysis.
    		 2 L8WU26 L8WU26