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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 290257: 2,4-dienoyl-coa reductase (Nadph)

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2,4-dienoyl-CoA reductase (NADPH). [EC: 1.3.1.34]
Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5- tetradehydroacyl-CoA + NADPH.
  • Best substrates for reduction contain a 2,4-diene structure with chain length C(8) or C(10).
 546 A0A010TB53 A0A010TB53 A0A023CAV6 A0A023CAV6 A0A023WTL7 A0A023WTL7 A0A023Z3B7 A0A023Z3B7 A0A024HKM4 A0A024HKM4
(536 more...)
2-enoate reductase. [EC: 1.3.1.31]
Butanoate + NAD(+) = but-2-enoate + NADH.
  • Acts, in the reverse direction, on a wide range of alkyl and aryl alpha-beta-unsaturated carboxylate ions; 2-butenoate was the best substrate tested.
 2 U2EIH0 U2EIH0