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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 289465: Glyceraldehyde-3-phosphate dehydrogenase, type II

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating). [EC: 1.2.1.59]
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)(+) = 3-phospho-D- glyceroyl phosphate + NAD(P)H.
  • NAD(+) and NADP(+) can be used as cofactors with similar efficiency, unlike EC 1.2.1.12 and EC 1.2.1.13, which are NAD(+)- and NADP(+)- dependent, respectively.
 1054 A0A031G310 A0A031G310 A0A031LRA1 A0A031LRA1 A0A059TUH5 A0A059TUH5 A0A062V534 A0A062V534 A0A063ZAN3 A0A063ZAN3
(1044 more...)
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). [EC: 1.2.1.12]
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
  • Also acts very slowly on D-glyceraldehyde and some other aldehydes.
  • Thiols can replace phosphate.
 18 A0A0A0HGI5 A0A0A0HGI5 A0A0E9LGS5 A0A0E9LGS5 A1W7V7 A1W7V7 A1W9A1 A1W9A1 C5T2Z2 C5T2Z2
(8 more...)