The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 288342: C-terminal binding protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 31 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 O46036 (/IPI) O88712 (/IPI) P56545 (/IPI) P56546 (/IPI) Q13363 (/IPI) Q5SQP8 (/IPI) Q5ZIZ6 (/IPI) Q9Z2F5 (/IPI)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
3 O46036 (/IPI) O88712 (/IPI) Q13363 (/IPI)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
2 O46036 (/IDA) P56546 (/IDA)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
2 O46036 (/TAS) Q9Z2F5 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 O46036 (/IPI) Q13363 (/IPI)
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
2 O88712 (/ISS) Q13363 (/ISS)
Repressing transcription factor binding GO:0070491
Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.
2 O46036 (/IPI) Q13363 (/IPI)
RNA polymerase II transcription corepressor activity GO:0001106
Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 Q13363 (/IDA)
RNA polymerase II transcription corepressor activity GO:0001106
Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 O88712 (/ISO)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 P56546 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 O88712 (/IDA)
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
1 O46036 (/IDA)
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
1 P56546 (/IGI)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 O46036 (/IMP)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 Q13363 (/TAS)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
1 O88712 (/ISO)
Transferase activity, transferring acyl groups GO:0016746
Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
1 Q9Z2F5 (/TAS)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 P56545 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 P56546 (/ISO)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q13363 (/IDA)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q13363 (/IPI)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 O88712 (/ISO)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 Q9Z2F5 (/IPI)
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P56545 (/IPI)
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P56546 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 O88712 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 O46036 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9Z2F5 (/IPI)
Retinoic acid receptor binding GO:0042974
Interacting selectively and non-covalently with the retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily.
1 P56546 (/IPI)
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
1 Q9Z2F5 (/IDA)
Repressing transcription factor binding GO:0070491
Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.
1 O88712 (/ISO)

There are 49 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Synapse assembly involved in innervation GO:0060386
The assembly of a synapse within a target tissue in which a nerve is invading.
13 F1QMW3 (/IGI) F1RA12 (/IGI) F8W377 (/IGI) F8W3Q3 (/IGI) F8W3U1 (/IGI) F8W438 (/IGI) F8W4E9 (/IGI) F8W509 (/IGI) F8W571 (/IGI) Q5BU17 (/IGI)
(3 more)
Clustering of voltage-gated calcium channels GO:0070073
The process in which voltage-gated calcium channels become localized together in high densities.
13 F1QMW3 (/IGI) F1RA12 (/IGI) F8W377 (/IGI) F8W3Q3 (/IGI) F8W3U1 (/IGI) F8W438 (/IGI) F8W4E9 (/IGI) F8W509 (/IGI) F8W571 (/IGI) Q5BU17 (/IGI)
(3 more)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
12 F1QMW3 (/IMP) F1RA12 (/IMP) F8W377 (/IMP) F8W3Q3 (/IMP) F8W3U1 (/IMP) F8W438 (/IMP) F8W4E9 (/IMP) F8W509 (/IMP) F8W571 (/IMP) Q6NZ25 (/IMP)
(2 more)
Regulation of gliogenesis GO:0014013
Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.
12 F1QMW3 (/IGI) F1RA12 (/IGI) F8W377 (/IGI) F8W3Q3 (/IGI) F8W3U1 (/IGI) F8W438 (/IGI) F8W4E9 (/IGI) F8W509 (/IGI) F8W571 (/IGI) Q6NZ25 (/IGI)
(2 more)
Regulation of gliogenesis GO:0014013
Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.
12 F1QMW3 (/IMP) F1RA12 (/IMP) F8W377 (/IMP) F8W3Q3 (/IMP) F8W3U1 (/IMP) F8W438 (/IMP) F8W4E9 (/IMP) F8W509 (/IMP) F8W571 (/IMP) Q6NZ25 (/IMP)
(2 more)
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
12 F1QMW3 (/IMP) F1RA12 (/IMP) F8W377 (/IMP) F8W3Q3 (/IMP) F8W3U1 (/IMP) F8W438 (/IMP) F8W4E9 (/IMP) F8W509 (/IMP) F8W571 (/IMP) Q6NZ25 (/IMP)
(2 more)
Regulation of melanocyte differentiation GO:0045634
Any process that modulates the frequency, rate or extent of melanocyte differentiation.
12 F1QMW3 (/IMP) F1RA12 (/IMP) F8W377 (/IMP) F8W3Q3 (/IMP) F8W3U1 (/IMP) F8W438 (/IMP) F8W4E9 (/IMP) F8W509 (/IMP) F8W571 (/IMP) Q6NZ25 (/IMP)
(2 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
7 P56545 (/ISS) Q0VCQ1 (/ISS) Q13363 (/ISS) Q9EQH5 (/ISS) Q9W758 (/ISS) Q9YHU0 (/ISS) Q9Z2F5 (/ISS)
White fat cell differentiation GO:0050872
The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.
6 P56545 (/ISS) Q0VCQ1 (/ISS) Q13363 (/ISS) Q9EQH5 (/ISS) Q9W758 (/ISS) Q9Z2F5 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
3 O46036 (/IDA) O88712 (/IDA) P56546 (/IDA)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 O88712 (/IMP) Q13363 (/IMP)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
2 P56545 (/TAS) Q13363 (/TAS)
Viral genome replication GO:0019079
Any process involved directly in viral genome replication, including viral nucleotide metabolism.
2 P56545 (/TAS) Q13363 (/TAS)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P56545 (/IMP) P56546 (/IMP)
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
2 E9QEQ4 (/IGI) Q9DEG7 (/IGI)
Positive regulation of retinoic acid receptor signaling pathway GO:0048386
Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
2 P56545 (/IMP) P56546 (/IMP)
White fat cell differentiation GO:0050872
The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.
2 O88712 (/IDA) P56546 (/IDA)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 O88712 (/ISO)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 O46036 (/TAS)
Embryonic development via the syncytial blastoderm GO:0001700
The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
1 O46036 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 O46036 (/IMP)
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 O46036 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q13363 (/TAS)
Wnt signaling pathway GO:0016055
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
1 O46036 (/IGI)
Sensory organ precursor cell fate determination GO:0016360
The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.
1 O46036 (/IMP)
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
1 O46036 (/IMP)
Regulation of Wnt signaling pathway GO:0030111
Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.
1 O46036 (/IMP)
Positive regulation of histone deacetylation GO:0031065
Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.
1 Q13363 (/IMP)
Positive regulation of histone deacetylation GO:0031065
Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.
1 O88712 (/ISO)
Negative regulation of histone acetylation GO:0035067
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.
1 Q13363 (/IMP)
Negative regulation of histone acetylation GO:0035067
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.
1 O88712 (/ISO)
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
1 O46036 (/IMP)
Positive regulation of chromatin binding GO:0035563
Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 P56546 (/IMP)
ATP-dependent chromatin remodeling GO:0043044
Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.
1 O46036 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 O46036 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P56546 (/IGI)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P56546 (/ISO)
Positive regulation of JAK-STAT cascade GO:0046427
Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
1 O46036 (/IMP)
Positive regulation of retinoic acid receptor signaling pathway GO:0048386
Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
1 P56546 (/ISO)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 Q13363 (/IMP)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 O88712 (/ISO)
Synapse assembly involved in innervation GO:0060386
The assembly of a synapse within a target tissue in which a nerve is invading.
1 Q5BU17 (/IMP)
Membrane fusion GO:0061025
The membrane organization process that joins two lipid bilayers to form a single membrane.
1 Q9Z2F5 (/TAS)
Clustering of voltage-gated calcium channels GO:0070073
The process in which voltage-gated calcium channels become localized together in high densities.
1 Q5BU17 (/IMP)
Negative regulation of histone H4 acetylation GO:0090241
Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
1 Q13363 (/IMP)
Negative regulation of histone H4 acetylation GO:0090241
Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
1 O88712 (/ISO)
Presynapse to nucleus signaling pathway GO:0099526
A series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).
1 Q9Z2F5 (/IMP)
Negative regulation of transcription from RNA polymerase II promoter by histone modification GO:1903758
A histone modification that results in negative regulation of transcription from RNA polymerase II promoter.
1 Q13363 (/IMP)
Negative regulation of transcription from RNA polymerase II promoter by histone modification GO:1903758
A histone modification that results in negative regulation of transcription from RNA polymerase II promoter.
1 O88712 (/ISO)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 O46036 (/IDA) O88712 (/IDA) P56545 (/IDA) P56546 (/IDA) Q13363 (/IDA) Q20595 (/IDA) Q5ZIZ6 (/IDA) Q9Z2F5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P56545 (/ISS) Q0VCQ1 (/ISS) Q13363 (/ISS) Q9EQH5 (/ISS) Q9W758 (/ISS) Q9YHU0 (/ISS) Q9Z2F5 (/ISS)
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
5 P56545 (/ISS) Q0VCQ1 (/ISS) Q13363 (/ISS) Q9EQH5 (/ISS) Q9Z2F5 (/ISS)
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
3 O88712 (/IDA) P56546 (/IDA) Q13363 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O88712 (/ISO) P56546 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q13363 (/IDA) X5D8Y5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9Z2F5 (/IMP)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 O88712 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q13363 (/TAS)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 O88712 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9Z2F5 (/IMP)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q5BU17 (/IDA)
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
1 O88712 (/ISO)
ISWI-type complex GO:0031010
Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.
1 O46036 (/IDA)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 P56546 (/IDA)
Ribbon synapse GO:0097470
Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.
1 P56546 (/IDA)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
1 Q9Z2F5 (/IDA)