The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 285747: Bifunctional polymyxin resistance protein ArnA

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
UDP-glucuronic acid oxidase (UDP-4-keto-hexauronic acid decarboxylating). [EC: 1.1.1.305]
UDP-alpha-D-glucuronate + NAD(+) = UDP-beta-L-threo-pentapyranos-4-ulose + CO(2) + NADH.
  • The activity is part of a bifunctional enzyme also performing the reaction of EC 2.1.2.13.
  • Formerly EC 1.1.1.n1.
2236 A0A010SJP6 A0A010SJP6 A0A014PRU6 A0A014PRU6 A0A017IE82 A0A017IE82 A0A022PPN6 A0A022PPN6 A0A023CG80 A0A023CG80
(2226 more...)
UDP-4-amino-4-deoxy-L-arabinose formyltransferase. [EC: 2.1.2.13]
10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinose.
  • The activity is part of a bifunctional enzyme also performing the reaction of EC 1.1.1.305.
  • Formerly EC 2.1.2.n1.
2230 A0A010SJP6 A0A010SJP6 A0A014PRU6 A0A014PRU6 A0A017IE82 A0A017IE82 A0A022PPN6 A0A022PPN6 A0A023CG80 A0A023CG80
(2220 more...)
UDP-glucuronate decarboxylase. [EC: 4.1.1.35]
UDP-D-glucuronate = UDP-D-xylose + CO(2).
    44 A0A127S1P7 A0A127S1P7 A0A1C0UF57 A0A1C0UF57 A0A1J0IGT5 A0A1J0IGT5 A0A1L3DF13 A0A1L3DF13 A0A1L4B1Q7 A0A1L4B1Q7
    (34 more...)
    DTDP-glucose 4,6-dehydratase. [EC: 4.2.1.46]
    dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O.
      10 D5X1W4 D5X1W4 D6CU45 D6CU45 Q0K0P7 Q0K0P7 S6ALJ9 S6ALJ9 S6APJ3 S6APJ3
      Methionyl-tRNA formyltransferase. [EC: 2.1.2.9]
      10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).
        6 A0A136M8B4 A0A136M8B4 A0A157TL68 A0A157TL68 A0A1K3F078 A0A1K3F078
        UDP-glucose 4-epimerase. [EC: 5.1.3.2]
        UDP-alpha-D-glucose = UDP-alpha-D-galactose.
        • Also acts on UDP-2-deoxyglucose.
        2 G0AH48 G0AH48