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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 248750: Glyoxylate/hydroxypyruvate reductase B

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Hydroxypyruvate reductase. [EC: 1.1.1.81]
D-glycerate + NAD(P)(+) = hydroxypyruvate + NAD(P)H.
    		 12 A0A086EJ85 A0A093SS75 A0A093V7X9 A0A094RUY7 A0A0B2W8K5 A0A0B3WQH1 A0A0B3YMF5 A0A0H3IC64 C6DJ88 D0KE36
    (2 more...)
    Glyoxylate reductase (NADP(+)). [EC: 1.1.1.79]
    Glycolate + NADP(+) = glyoxylate + NADPH.
    • Also reduces hydroxypyruvate to glycerate.
    • Has some affinity for NAD(+).
    		 12 A0A086EJ85 A0A093SS75 A0A093V7X9 A0A094RUY7 A0A0B2W8K5 A0A0B3WQH1 A0A0B3YMF5 A0A0H3IC64 C6DJ88 D0KE36
    (2 more...)