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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 231797: Phosphonate dehydrogenase (NAD-dependent phosphite...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphonate dehydrogenase. [EC: 1.20.1.1]
Phosphonate + NAD(+) + H(2)O = phosphate + NADH.
  • NADP(+) is a poor substitute for NAD(+) in the enzyme from Pseudomonas stutzeri WM88.
 48 A0A023CHB9 A0A024ELS2 A0A075P825 A0A078LUY1 A0A086BQI1 A0A087F9L9 A0A098FP75 A0A0A1GKA4 A0A0B5KJU9 A0A0C2S2M8
(38 more...)
Glyoxylate reductase (NADP(+)). [EC: 1.1.1.79]
Glycolate + NADP(+) = glyoxylate + NADPH.
  • Also reduces hydroxypyruvate to glycerate.
  • Has some affinity for NAD(+).
 13 A0A0E1CSI0 A0A0F0XIU5 A0A0M1TI47 A0A155J9C9 A0A1A0DTS9 A0A1C1PKX8 A0A1M1GS59 A6TI50 G7RUX3 J4WIA0
(3 more...)