The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136256: GDP-mannose 4,6-dehydratase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
GDP-mannose 4,6-dehydratase. [EC: 4.2.1.47]
GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H(2)O.
  • Forms the first step in the biosynthesis of GDP-alpha-D-rhamnose and GDP-alpha-L-fucose.
  • In Aneurinibacillus thermoaerophilus L420-91T, this enzyme acts as a bifunctional enzyme, catalyzing the above reaction as well as the reaction catalyzed by EC 1.1.1.281.
16 A0A069PXN8 A0A080VGB8 A0A0E1B3V8 A0A0H2ZJC0 A0A0H3QND0 A0A0P1DIZ3 A0A157VM70 A0A1C7BI06 A0A1D5BUE9 A0A1E9CBT8
(6 more...)