The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 88725: Tyrosine--tRNA ligase, cytoplasmic

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Tyrosine--tRNA ligase. [EC: 6.1.1.1]
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).
    3116 A0A010QVI0 A0A010QVI0 A0A015LRZ7 A0A015LRZ7 A0A016S5E9 A0A016S5E9 A0A017SRB8 A0A017SRB8 A0A022VYX0 A0A022VYX0
    (3106 more...)
    Tryptophan--tRNA ligase. [EC: 6.1.1.2]
    ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).
      2 A0A1M4MIV7 A0A1M4MIV7
      Isoleucine--tRNA ligase. [EC: 6.1.1.5]
      ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).
        2 A0A170XYW6 A0A170XYW6