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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 634589: Putative bifunctional polynucleotide phosphatase/k...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Polynucleotide 5'-hydroxyl-kinase. [EC: 2.7.1.78]
ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.
  • Also acts on 5'-dephospho-RNA 3'-mononucleotides.
 9 A0A0U2K3G3 A0A1E1ETH9 B7PJU9 E3VY87 J3IZA4 O13911 Q5UQD2 Q96T60 Q9JLV6
Polynucleotide 3'-phosphatase. [EC: 3.1.3.32]
A 3'-phosphopolynucleotide + H(2)O = a polynucleotide + phosphate.
  • Also hydrolyzes nucleoside 2'-, 3'- and 5'-monophosphates, but only 2'- and 3'-phosphopolynucleotides.
 9 A0A0U2K3G3 A0A1E1ETH9 B7PJU9 E3VY87 J3IZA4 O13911 Q5UQD2 Q96T60 Q9JLV6