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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 627793: Thymidine kinase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Thymidine kinase. [EC: 2.7.1.21]
ATP + thymidine = ADP + thymidine 5'-phosphate.
  • Deoxyuridine can also act as acceptor.
  • dGTP can also act as donor.
  • The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyzes this reaction as well as those of EC 2.7.1.114, EC 2.7.1.118, and EC 2.7.4.9.
  • Formerly EC 2.7.1.75.
 440 A0A059TAU5 A0A059TAU6 A0A059TAZ0 A0A060D187 A0A060D2X1 A0A060Q1U8 A0A068FNV1 A0A068FS13 A0A076JY19 A0A077B9Q8
(430 more...)