# STOCKHOLM 1.0
#=GF ID 3.40.50.2300/FF/152323
#=GF DE Two-component system response regulator
#=GF AC 3.40.50.2300/FF/152323
#=GF TP FunFam
#=GF DR CATH: 4.2
#=GF DR DOPS: 70.862
#=GS P9WGL7/3-132       AC P9WGL7
#=GS P9WGL7/3-132       OS Mycobacterium tuberculosis H37Rv
#=GS P9WGL7/3-132       DE Uncharacterized response regulatory protein Rv3143
#=GS P9WGL7/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS P9WGL7/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS P9WGL7/3-132       DR GO; GO:0005618; 
#=GS H9L4Q6/1-133       AC H9L4Q6
#=GS H9L4Q6/1-133       OS Vibrio cholerae O1 biovar El Tor str. N16961
#=GS H9L4Q6/1-133       DE Response regulator VieA
#=GS H9L4Q6/1-133       DR GENE3D; 3ec0f0f165c4a5ee707800ff3f3f5d70/1-133; 
#=GS H9L4Q6/1-133       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS I6YFD5/3-132       AC I6YFD5
#=GS I6YFD5/3-132       OS Mycobacterium tuberculosis H37Rv
#=GS I6YFD5/3-132       DE Chemotaxis protein CheY
#=GS I6YFD5/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS I6YFD5/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS O68318/1-133       AC O68318
#=GS O68318/1-133       OS Vibrio cholerae
#=GS O68318/1-133       DE Response regulator
#=GS O68318/1-133       DR GENE3D; 3ec0f0f165c4a5ee707800ff3f3f5d70/1-133; 
#=GS O68318/1-133       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS O68318/1-133       DR GO; GO:0000156; GO:0000160; 
#=GS A0A0H5Z238/1-131   AC A0A0H5Z238
#=GS A0A0H5Z238/1-131   OS Vibrio cholerae
#=GS A0A0H5Z238/1-131   DE Response regulator VieA
#=GS A0A0H5Z238/1-131   DR GENE3D; 1819978976e0a2761597492eab3c6a66/1-131; 
#=GS A0A0H5Z238/1-131   DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS C3LMX8/1-133       AC C3LMX8
#=GS C3LMX8/1-133       OS Vibrio cholerae M66-2
#=GS C3LMX8/1-133       DE Response regulator VieA
#=GS C3LMX8/1-133       DR GENE3D; 3ec0f0f165c4a5ee707800ff3f3f5d70/1-133; 
#=GS C3LMX8/1-133       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS A0A0H5Y800/15-157  AC A0A0H5Y800
#=GS A0A0H5Y800/15-157  OS Vibrio cholerae
#=GS A0A0H5Y800/15-157  DE Response regulator VieA
#=GS A0A0H5Y800/15-157  DR GENE3D; 462e156b7ba3e863d9915c5e1e20f806/15-157; 
#=GS A0A0H5Y800/15-157  DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS A0A0H3AM52/1-133   AC A0A0H3AM52
#=GS A0A0H3AM52/1-133   OS Vibrio cholerae O395
#=GS A0A0H3AM52/1-133   DE Response regulator VieA
#=GS A0A0H3AM52/1-133   DR GENE3D; 5548c1233e1a5cdfff4cab4dc11e522a/1-133; 
#=GS A0A0H3AM52/1-133   DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio cholerae; 
#=GS D0IK75/1-135       AC D0IK75
#=GS D0IK75/1-135       OS Vibrio sp. RC586
#=GS D0IK75/1-135       DE Response regulator VieA
#=GS D0IK75/1-135       DR GENE3D; 64b6c31db0a8710f3f3179713dd3d436/1-135; 
#=GS D0IK75/1-135       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio sp. RC586; 
#=GS D0HH55/2-136       AC D0HH55
#=GS D0HH55/2-136       OS Vibrio mimicus VM223
#=GS D0HH55/2-136       DE Response regulator VieA
#=GS D0HH55/2-136       DR GENE3D; 69b6012e60d162b74264df71ff975cc5/2-136; 
#=GS D0HH55/2-136       DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio mimicus; 
#=GS A0A0Q0TCK3/1-125   AC A0A0Q0TCK3
#=GS A0A0Q0TCK3/1-125   OS Vibrio metoecus
#=GS A0A0Q0TCK3/1-125   DE Diguanylate phosphodiesterase
#=GS A0A0Q0TCK3/1-125   DR GENE3D; a6d6d352a40b398b625d2e8cf4892946/1-125; 
#=GS A0A0Q0TCK3/1-125   DR ORG; Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio; Vibrio metoecus; 
#=GS M8CI91/3-132       AC M8CI91
#=GS M8CI91/3-132       OS Mycobacterium orygis 112400015
#=GS M8CI91/3-132       DE Response regulator
#=GS M8CI91/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS M8CI91/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium orygis; 
#=GS A0A197ISS4/3-132   AC A0A197ISS4
#=GS A0A197ISS4/3-132   OS Mycobacterium mungi
#=GS A0A197ISS4/3-132   DE Uncharacterized protein
#=GS A0A197ISS4/3-132   DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A0A197ISS4/3-132   DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium mungi; 
#=GS A0A045JC76/3-132   AC A0A045JC76
#=GS A0A045JC76/3-132   OS Mycobacterium tuberculosis
#=GS A0A045JC76/3-132   DE Response regulator
#=GS A0A045JC76/3-132   DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A0A045JC76/3-132   DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS A0A0H3P7H1/3-132   AC A0A0H3P7H1
#=GS A0A0H3P7H1/3-132   OS Mycobacterium bovis AF2122/97
#=GS A0A0H3P7H1/3-132   DE PROBABLE RESPONSE REGULATOR
#=GS A0A0H3P7H1/3-132   DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A0A0H3P7H1/3-132   DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium bovis; 
#=GS G0THB5/3-132       AC G0THB5
#=GS G0THB5/3-132       OS Mycobacterium canettii CIPT 140010059
#=GS G0THB5/3-132       DE Putative response regulator
#=GS G0THB5/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS G0THB5/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium canettii; 
#=GS A0A083VYH6/3-132   AC A0A083VYH6
#=GS A0A083VYH6/3-132   OS Mycobacterium bovis
#=GS A0A083VYH6/3-132   DE Response regulator
#=GS A0A083VYH6/3-132   DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A0A083VYH6/3-132   DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium bovis; 
#=GS A0A109SRK5/3-132   AC A0A109SRK5
#=GS A0A109SRK5/3-132   OS Mycobacterium microti
#=GS A0A109SRK5/3-132   DE Response regulator
#=GS A0A109SRK5/3-132   DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A0A109SRK5/3-132   DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium microti; 
#=GS R4M6E8/3-132       AC R4M6E8
#=GS R4M6E8/3-132       OS Mycobacterium tuberculosis str. Haarlem/NITR202
#=GS R4M6E8/3-132       DE Response regulator
#=GS R4M6E8/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS R4M6E8/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS A0A0H3MAG8/3-132   AC A0A0H3MAG8
#=GS A0A0H3MAG8/3-132   OS Mycobacterium bovis BCG str. Pasteur 1173P2
#=GS A0A0H3MAG8/3-132   DE Probable response regulator
#=GS A0A0H3MAG8/3-132   DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A0A0H3MAG8/3-132   DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium bovis; 
#=GS P9WGL6/3-132       AC P9WGL6
#=GS P9WGL6/3-132       OS Mycobacterium tuberculosis CDC1551
#=GS P9WGL6/3-132       DE Uncharacterized response regulatory protein MT3230
#=GS P9WGL6/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS P9WGL6/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS A5U7F9/3-132       AC A5U7F9
#=GS A5U7F9/3-132       OS Mycobacterium tuberculosis H37Ra
#=GS A5U7F9/3-132       DE Uncharacterized protein
#=GS A5U7F9/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A5U7F9/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS A0A0G4DZ18/3-132   AC A0A0G4DZ18
#=GS A0A0G4DZ18/3-132   OS Mycobacterium caprae
#=GS A0A0G4DZ18/3-132   DE Uncharacterized response regulatory protein Rv314 3/MT3230
#=GS A0A0G4DZ18/3-132   DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A0A0G4DZ18/3-132   DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium caprae; 
#=GS F8M654/3-132       AC F8M654
#=GS F8M654/3-132       OS Mycobacterium africanum GM041182
#=GS F8M654/3-132       DE Putative response regulator
#=GS F8M654/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS F8M654/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium africanum; 
#=GS A0A0H3LF14/3-132   AC A0A0H3LF14
#=GS A0A0H3LF14/3-132   OS Mycobacterium tuberculosis str. Erdman = ATCC 35801
#=GS A0A0H3LF14/3-132   DE Response regulator
#=GS A0A0H3LF14/3-132   DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS A0A0H3LF14/3-132   DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GS R4MKV7/3-132       AC R4MKV7
#=GS R4MKV7/3-132       OS Mycobacterium tuberculosis CAS/NITR204
#=GS R4MKV7/3-132       DE Response regulator
#=GS R4MKV7/3-132       DR GENE3D; d778de934c320c4ca8e6080850b66077/3-132; 
#=GS R4MKV7/3-132       DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; 
#=GF TC 155.5 2.5E-49
#=GF SQ 26
P9WGL7/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
H9L4Q6/1-133               --------MKIMIVEDDRIQATSLKLKLRQLG------LDDVILAE--NGFAALELCNKVGIDLMFCDIRMPQMDGISLLSQLSLQAPKL-GVVILSAVEDTILELTHNMCSLAGFAYVDRLPKPYEVEDLQRVVEGFQKQTEPETSHKP--
I6YFD5/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
O68318/1-133               --------MKIMIVEDDRIQATSLKLKLRQLG------LDDVILAE--NGFAALELCNKVGIDLMFCDIRMPQMDGISLLSQLSLQAPKL-GVVILSAVEDTILELTHNMCSLAGFAYVDRLPKPYEVEDLQRVVEGFQKQTEPETSHKP--
A0A0H5Z238/1-131           --------MKIMIVEDDRIQATSLKLKLRQLG------LDDVILAE--NGFAALELCNKVGIDLMFCDIRMPQMDGISLLSQLSLQAPKL-GVVIFSAVEDTILELTHNMCSLAGFAYVDRLPKPYEVEDLQRVVEGFQKQTEPETSH----
C3LMX8/1-133               --------MKIMIVEDDRIQATSLKLKLRQLG------LDDVILAE--NGFAALELCNKVGIDLMFCDIRMPQMDGISLLSQLSLQAPKL-GVVILSAVEDTILELTHNMCSLAGFAYVDRLPKPYEVEDLQRVVEGFQKQTEPETSHKP--
A0A0H5Y800/15-157          ISIRANNVMKIMIVEDDRIQATSLKLKLRQLG------LDDVILAE--NGFAALELCNKVGIDLMFCDIRMPQMDGISLLSQLSLQAPKL-GVVILSAVEDTILELTHNMCSLAGFAYVDRLPKPYEVEDLQRVVEGFQKQTEPETSHKXXX
A0A0H3AM52/1-133           --------MKIMIVEDDRIQATSLKLKLRQLG------LDDVILAE--NGFAALELCNKVGIDLMFCDIRMPQMDGISLLSQLSLQAPKL-GVVILSAVEDTILELTHNMCSLAGFAYVDRLPKPYEVEDLQRVVEGFQKQTEPETSHKP--
D0IK75/1-135               --------MKIMIVEDDRIQATSLRLKLRQLG------LDEVILAE--NGFAALELSNKVGVDLMFCDIRMPHMDGISLLSQLSERAPKL-GVVVLSAVDDAILELTRNMCSLAGFSFVERLSKPYEVKDLQRVIERFQKQAQPKTDECKST
D0HH55/2-136               ---RVNNLMKILIVEDDRIQATSLKLKLRHLG------LNEVILAE--NGFAALELCNKVGIDLIFCDIRMPQMDGISLLSQLGEHFPKL-GVIILSAVDDAILELTRNMCSLAGFPFVDSLSKPYQMEELQRVIESFQEQARPEIS-----
A0A0Q0TCK3/1-125           -----------MIVEDDRIQATSLKLKLRQLG------MDEVILAE--NGFAALELCNKVDIDLMFCDIRMPHMDGISLLSKLSEQYPKL-GVIILSAVDDAVLELTRNMCSLAGFAYIDSLSKPYEVEDLQQVIDGFQKQSLPE-------
M8CI91/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A0A197ISS4/3-132           ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A0A045JC76/3-132           ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A0A0H3P7H1/3-132           ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
G0THB5/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A0A083VYH6/3-132           ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A0A109SRK5/3-132           ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
R4M6E8/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A0A0H3MAG8/3-132           ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
P9WGL6/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A5U7F9/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A0A0G4DZ18/3-132           ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
F8M654/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
A0A0H3LF14/3-132           ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
R4MKV7/3-132               ---DSSTALRILVYSDN---VQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAA-------VPHPVDPIVLGRTVLSLLRA--PA-------
#=GC scorecons             00022222567674596222656454469599222222857665692269556655467588995549455655696665589545465425767866449455456465555922112216769465449585745656511951110000
#=GC scorecons_70          __________***__**__________**_**______*_**___*___*___*___**_****___*_______**_*__**_________*_**____*____________*_______**_*_*___*_*_*__*_*___*________
#=GC scorecons_80          __________*____*____________*_**______*_*____*___*__________****___*_______*_____**____________*____*____________*________*_*_____*_*_*________*________
#=GC scorecons_90          _______________*____________*_**______*______*___*__________****___*_______*_____**____________*____*____________*__________*_____*_*__________*________
//