The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18602: Hypoxanthine guanine phosphoribosyltransferase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Hypoxanthine phosphoribosyltransferase. [EC: 2.4.2.8]
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
  • Guanine and 6-mercaptopurine can replace hypoxanthine.
4574 A0A009EQK5 A0A009H1A7 A0A009H2R6 A0A009H5Q4 A0A009HNL1 A0A009K2V1 A0A009K729 A0A009KJ40 A0A009NAK7 A0A009Q6J0
(4564 more...)
TRNA(Ile)-lysidine synthetase. [EC: 6.3.4.19]
(tRNA(Ile2))-cytidine(34) + L-lysine + ATP = (tRNA(Ile2))-lysidine(34) + AMP + diphosphate + H(2)O.
  • The bacterial enzyme modifies the wobble base of the CAU anticodon of tRNA(Ile) at the oxo group in position 2 of cytidine(34).
  • This modification determines both codon and amino acid specificities of tRNA(Ile).
133 A0A023PEW0 A0A062X4Y0 A0A078M4J0 A0A089LZB9 A0A0A3VXV1 A0A0B8R7R5 A0A0D0HJL8 A0A0D0RCA4 A0A0D0RNS5 A0A0D1NQS9
(123 more...)
Xanthine phosphoribosyltransferase. [EC: 2.4.2.22]
XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine.
    2 A0A1J4KSN0 P51900