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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115030: 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxonona...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-hydroxy-6-oxonona-2,4-dienedioate hydrolase. [EC: 3.7.1.14]
(1) (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H(2)O = (2Z)-2- hydroxypenta-2,4-dienoate + succinate. (2) (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate + H(2)O = (2Z)-2-hydroxypenta-2,4-dienoate + fumarate.
  • This enzyme catalyzes a step in a pathway of phenylpropanoid compounds degradation.
  • The first step of the enzyme mechanism involves a reversible keto- enol tautomerization.
  • Formerly EC 3.7.1.n1.
 443 A0A023C9B6 A0A023V9T6 A0A023YT50 A0A024KSQ8 A0A024L715 A0A025C9Z6 A0A026RXF4 A0A026V4V9 A0A027TBF0 A0A028AKG3
(433 more...)
2,6-dioxo-6-phenylhexa-3-enoate hydrolase. [EC: 3.7.1.8]
2,6-dioxo-6-phenylhexa-3-enoate + H(2)O = benzoate + 2-oxopent-4-enoate.
  • Cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 1.13.11.39 by ring-fission at a -CO-C bond.
  • Involved in the breakdown of biphenyl-related compounds by Pseudomonas sp.
 52 A0A045KDP6 A0A076PQV4 A0A097SRG5 A0A0D8HUL7 A0A0H3LJQ0 A0A0H3M9X6 A0A0H3P682 A0A0K1JC77 A0A0P0UW49 A0A0T2YW73
(42 more...)
4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase. [EC: 3.7.1.17]
(1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4- oate + H(2)O = 3-((3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4- yl)propanoate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate.
  • The enzyme is involved in the bacterial degradation of the steroid ring structure, and is involved in degradation of multiple steroids, such as testosterone, cholesterol, and sitosterol.
 23 A0A045KDP6 A0A0H3LJQ0 A0A0H3M9X6 A0A0H3P682 A0A0K2YFK8 A0A0U3JV64 A0A109SSR5 A0A197IV45 A0A1A9ECQ8 A0A1B1JYY0
(13 more...)
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