The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 57526: Ribosomal RNA methyltransferase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA (guanine(1835)-N(2))-methyltransferase. [EC: 2.1.1.174]
S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(1835) in 23S rRNA.
  • The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.
  • The enzyme specifically methylates guanine(1835) at N(2) in 23S rRNA.
  • Formerly EC 2.1.1.52.
11 A0A063XBK3 A0A0K6JSI7 A0A0K6LLR6 A0A0T8PWB8 A0A125UD98 A0A199WBH4 G4F0R6 L8AC65 M4KMB7 P37872
(1 more...)
16S rRNA (guanine(966)-N(2))-methyltransferase. [EC: 2.1.1.171]
S-adenosyl-L-methionine + guanine(966) in 16S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(966) in 16S rRNA.
  • The enzyme efficiently methylates guanine(966) of the assembled 30S subunits in vitro.
  • Protein-free 16S rRNA is not a substrate for RsmD.
  • The enzyme specifically methylates guanine(966) at N(2) in 16S rRNA.
  • Formerly EC 2.1.1.52.
8 A0A063XBK3 A0A125UD98 A0A199WBH4 G4F0R6 L8AC65 M4KMB7 P37872 U1Z2T3
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