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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135578: C-5 cytosine-specific DNA methylase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DNA (cytosine-5-)-methyltransferase. [EC: 2.1.1.37]
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
  • Formerly EC 2.1.1.73.
 3287 A0A011TG01 A0A014L7M7 A0A014NA45 A0A015TYZ4 A0A015WFL3 A0A015WM36 A0A015ZNA5 A0A016AV74 A0A016BYI4 A0A016GBY6
(3277 more...)
Repressor LexA. [EC: 3.4.21.88]
Hydrolysis of Ala-|-Gly bond in repressor LexA.
  • In the presence of single-stranded DNA, the RecA protein interacts with LexA causing an autocatalytic cleavage which disrupts the DNA- binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  • The activity was previously attributed to the RecA protein (formerly EC 3.4.99.37).
  • Belongs to peptidase family S24.
 5 A0A0G0CZ33 A0A0G0EX51 A0A0G0QRU0 A0A0G0VWY5 A0A0G0XQY0