The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate/ornithine carbamoyltransferase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8172: Ornithine carbamoyltransferase, catabolic

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ornithine carbamoyltransferase. [EC: 2.1.3.3]
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
  • The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.
11341 A0A009FCR8 A0A009H9A3 A0A009H9A5 A0A009I4A2 A0A009IG97 A0A009KBU0 A0A009KJG0 A0A009KMZ7 A0A009NLX4 A0A009QB43
(11331 more...)
Putrescine carbamoyltransferase. [EC: 2.1.3.6]
Carbamoyl phosphate + putrescine = phosphate + N-carbamoylputrescine.
  • The plant enzyme also catalyzes the reactions of EC 2.1.3.3, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.
7 A0A010ZCM7 A0A117M9A8 C0WN35 C0XJB3 C2CZ50 F8J9E7 X0PM19
Acetylornithine transaminase. [EC: 2.6.1.11]
N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
  • Also acts on L-ornithine and N(2)-succinyl-L-ornithine.
2 A0A068NTF5 B8KNC7
N-acetylornithine carbamoyltransferase. [EC: 2.1.3.9]
Carbamoyl phosphate + N(2)-acetyl-L-ornithine = phosphate + N-acetyl-L- citrulline.
  • Differs from EC 2.1.3.3.
  • This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate.
1 A0A151AWA0