# STOCKHOLM 1.0 #=GF ID 3.40.50.10810/FF/9008 #=GF DE Bifunctional helicase and thymine dioxygenase JBP2 #=GF AC 3.40.50.10810/FF/9008 #=GF TP FunFam #=GF DR CATH: 4.2 #=GF DR DOPS: 65.438 #=GS Q57X81/494-746 AC Q57X81 #=GS Q57X81/494-746 OS Trypanosoma brucei brucei TREU927 #=GS Q57X81/494-746 DE Bifunctional helicase and thymine dioxygenase JBP2 #=GS Q57X81/494-746 DR GENE3D; 26bea9ccd56174faf8534e96e00112f6/494-746; #=GS Q57X81/494-746 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q57X81/494-746 DR GO; GO:0005634; GO:0050341; GO:0070580; #=GS Q57X81/494-746 DR EC; 1.14.11.6; 3.6.4.12; #=GS B6EU02/511-757 AC B6EU02 #=GS B6EU02/511-757 OS Leishmania tarentolae #=GS B6EU02/511-757 DE Bifunctional helicase and thymine dioxygenase JBP2 #=GS B6EU02/511-757 DR GENE3D; a4ecbeeb1c652b6cd6275d6d4c2d227c/511-757; #=GS B6EU02/511-757 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania tarentolae; #=GS B6EU02/511-757 DR GO; GO:0005634; GO:0050341; GO:0070580; #=GS B6EU02/511-757 DR EC; 1.14.11.6; 3.6.4.12; #=GS Q4QFY1/512-755 AC Q4QFY1 #=GS Q4QFY1/512-755 OS Leishmania major #=GS Q4QFY1/512-755 DE Bifunctional helicase and thymine dioxygenase JBP2 #=GS Q4QFY1/512-755 DR GENE3D; 0b8c35c2e5ace204279a610cf4bd8414/512-755; #=GS Q4QFY1/512-755 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS Q4QFY1/512-755 DR EC; 1.14.11.6; 3.6.4.12; #=GS D6XIZ6/494-746 AC D6XIZ6 #=GS D6XIZ6/494-746 OS Trypanosoma brucei brucei TREU927 #=GS D6XIZ6/494-746 DE SNF2 DNA repair protein, putative #=GS D6XIZ6/494-746 DR GENE3D; 26bea9ccd56174faf8534e96e00112f6/494-746; #=GS D6XIZ6/494-746 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS D6XIZ6/494-746 DR EC; 1.14.11.6; 3.6.4.12; #=GS A0A1G4IJ49/494-746 AC A0A1G4IJ49 #=GS A0A1G4IJ49/494-746 OS Trypanosoma equiperdum #=GS A0A1G4IJ49/494-746 DE SNF2 DNA repair protein, putative #=GS A0A1G4IJ49/494-746 DR GENE3D; 26bea9ccd56174faf8534e96e00112f6/494-746; #=GS A0A1G4IJ49/494-746 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; #=GS A0A1G4IJ49/494-746 DR EC; 1.14.11.6; 3.6.4.12; #=GS A4H7G5/511-759 AC A4H7G5 #=GS A4H7G5/511-759 OS Leishmania braziliensis #=GS A4H7G5/511-759 DE Bifunctional helicase and thymine dioxygenase JBP2 #=GS A4H7G5/511-759 DR GENE3D; b50986b0891b6fe41e1eb94ee1d44e6d/511-759; #=GS A4H7G5/511-759 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A4H7G5/511-759 DR EC; 1.14.11.6; 3.6.4.12; #=GS Q4DCH3/489-729 AC Q4DCH3 #=GS Q4DCH3/489-729 OS Trypanosoma cruzi strain CL Brener #=GS Q4DCH3/489-729 DE Bifunctional helicase and thymine dioxygenase JBP2 #=GS Q4DCH3/489-729 DR GENE3D; e628a28f16708aec5c2d07ea21481b5c/489-729; #=GS Q4DCH3/489-729 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Schizotrypanum; Trypanosoma cruzi; #=GS Q4DCH3/489-729 DR EC; 1.14.11.6; 3.6.4.12; #=GS A4HVU6/512-757 AC A4HVU6 #=GS A4HVU6/512-757 OS Leishmania infantum #=GS A4HVU6/512-757 DE Bifunctional helicase and thymine dioxygenase JBP2 #=GS A4HVU6/512-757 DR GENE3D; f1e99db4ad1dcce5ab21436656c2f7bb/512-757; #=GS A4HVU6/512-757 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS A4HVU6/512-757 DR EC; 1.14.11.6; 3.6.4.12; #=GS E9BBN9/436-681 AC E9BBN9 #=GS E9BBN9/436-681 OS Leishmania donovani BPK282A1 #=GS E9BBN9/436-681 DE J-binding protein, putative #=GS E9BBN9/436-681 DR GENE3D; 15b9a9cb11a6b150e5962f63aace407b/436-681; #=GS E9BBN9/436-681 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A0A1E1IRJ8/511-759 AC A0A1E1IRJ8 #=GS A0A1E1IRJ8/511-759 OS Leishmania guyanensis #=GS A0A1E1IRJ8/511-759 DE J-binding protein, putative #=GS A0A1E1IRJ8/511-759 DR GENE3D; 1c90b8b94a45d000ee77cc8256c654db/511-759; #=GS A0A1E1IRJ8/511-759 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; #=GS A0A088RKQ1/511-759 AC A0A088RKQ1 #=GS A0A088RKQ1/511-759 OS Leishmania panamensis #=GS A0A088RKQ1/511-759 DE J-binding protein, putative #=GS A0A088RKQ1/511-759 DR GENE3D; 1c90b8b94a45d000ee77cc8256c654db/511-759; #=GS A0A088RKQ1/511-759 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; #=GS E9APJ8/436-681 AC E9APJ8 #=GS E9APJ8/436-681 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9APJ8/436-681 DE Putative j-binding protein #=GS E9APJ8/436-681 DR GENE3D; 267144e5c7928eb79f2e2d69cce34389/436-681; #=GS E9APJ8/436-681 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS A0A061J8N3/488-746 AC A0A061J8N3 #=GS A0A061J8N3/488-746 OS Trypanosoma rangeli SC58 #=GS A0A061J8N3/488-746 DE SNF2 DNA repair protein #=GS A0A061J8N3/488-746 DR GENE3D; 4a2372890afdc628a4fb6444f7b97c25/488-746; #=GS A0A061J8N3/488-746 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Herpetosoma; Trypanosoma rangeli; #=GS K2M079/487-738 AC K2M079 #=GS K2M079/487-738 OS Trypanosoma cruzi marinkellei #=GS K2M079/487-738 DE SNF2 DNA repair protein, putative #=GS K2M079/487-738 DR GENE3D; 4a66fcad7ad9dc4b8ef646eea9a71e7d/487-738; #=GS K2M079/487-738 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Schizotrypanum; Trypanosoma cruzi; Trypanosoma cruzi marinkellei; #=GS Q4DUV6/389-629 AC Q4DUV6 #=GS Q4DUV6/389-629 OS Trypanosoma cruzi strain CL Brener #=GS Q4DUV6/389-629 DE SNF2 DNA repair protein, putative #=GS Q4DUV6/389-629 DR GENE3D; 4c417a1851c8224bafa61236ae59874d/389-629; #=GS Q4DUV6/389-629 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Schizotrypanum; Trypanosoma cruzi; #=GS V5BHQ6/489-729 AC V5BHQ6 #=GS V5BHQ6/489-729 OS Trypanosoma cruzi Dm28c #=GS V5BHQ6/489-729 DE SNF2 DNA repair protein #=GS V5BHQ6/489-729 DR GENE3D; 9370d88a97a6b9c0bb33c157212b6094/489-729; #=GS V5BHQ6/489-729 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Schizotrypanum; Trypanosoma cruzi; #=GF TC 427.2 1.1E-131 #=GF SQ 16 Q57X81/494-746 ---------DSVVNLNGVTGHLPPLCIPFKIAKTLSLTQHAALRFVSRRIKEGDGCVLALTMGLGKTLVSLTICYSYIYNNGPCDILIVAPKTLLQHWMQEAKKWKDYGLVFPGFIVLNNVDSSSFEDDLSNYEQQGTTTNPKKSYVFVINPGYIKSFLSRVKGFRPALIVVDEGHCISSKESKLREVLDSLYCSARVVLTGTPVQNNAEELYRLVGWVDDKVHSTLPQRDFNEFSNSINRYVNGDDSAFCDALFAQRYIHE B6EU02/511-757 --LRNTEVLNTTVNINGADSSLPPLFVPTRLASHLAPVQLAALGFIVERTEKQSGCVVAMTMGLGKTLVALTLCFSQLHLAPQADILILTPKPIISHWVDEKNKWAMHGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKLGHVFVINGEYLAGFLRRFKRFTPLLIIVDEGHRVAAKGNKLTESLDRLRCNLRIVLSGTPLQNDASELYRLVGWVNKGVGRVLPPKRFQELANDINQFVEGDDGA------------- Q4QFY1/512-755 ---LNTEVRNTTVNINGADSSLPPLFVPTRLASHLAPVQLAALGFIVERTEKQSGCVVAMTMGLGKTLVALTLCFSQLYLAPQADILILTPKPIISHWVDEKNKWGMHGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKSGHIFVINGEYLAGFLRRFKRFTPLVMIVDEGHRVAAKGNKLTESLDRLRCNLRIVLSGTPLQNDASELYRLVGWVNKGVSRVLPPKRFQELANDINQFVEGDD--------------- D6XIZ6/494-746 ---------DSVVNLNGVTGHLPPLCIPFKIAKTLSLTQHAALRFVSRRIKEGDGCVLALTMGLGKTLVSLTICYSYIYNNGPCDILIVAPKTLLQHWMQEAKKWKDYGLVFPGFIVLNNVDSSSFEDDLSNYEQQGTTTNPKKSYVFVINPGYIKSFLSRVKGFRPALIVVDEGHCISSKESKLREVLDSLYCSARVVLTGTPVQNNAEELYRLVGWVDDKVHSTLPQRDFNEFSNSINRYVNGDDSAFCDALFAQRYIHE A0A1G4IJ49/494-746 ---------DSVVNLNGVTGHLPPLCIPFKIAKTLSLTQHAALRFVSRRIKEGDGCVLALTMGLGKTLVSLTICYSYIYNNGPCDILIVAPKTLLQHWMQEAKKWKDYGLVFPGFIVLNNVDSSSFEDDLSNYEQQGTTTNPKKSYVFVINPGYIKSFLSRVKGFRPALIVVDEGHCISSKESKLREVLDSLYCSARVVLTGTPVQNNAEELYRLVGWVDDKVHSTLPQRDFNEFSNSINRYVNGDDSAFCDALFAQRYIHE A4H7G5/511-759 --LLNTEIRHTTVNINEADSSLPPLFVPTRLASQLAPVQLAALGFIVERTNKQSGCVVAMTMGLGKTLVALTLCFSHLHLAPQADILILTPKPIISHWVDEKNKWGMYGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKAGHVFVINSEYLAGFLRRFRRFTPFLIIVDEGHRVAAKGNKLTESLDRLRCNLRVVLSGTPLQNDASELYRLVGWVNKGVSKVLPPKRFQELANSINQFVEGDDGAF--------Y--- Q4DCH3/489-729 --RLLDRSRQSVINLNATDPNLPPIYLPGRLLEVLSPVQQAALGFVVDRLSKGNGCVIALTMGLGKTLLSLALCYSHMYDQNPRDVLILAPKIVLTHWTGEKQKWEKYGLVFSHFVVSDGTDSVSFEIALKRYKQQLNGELPRTSHVFVINPEYIRTVLKKLTGFRPSLIIVDEGHRVSSKGSKLKDWLEGLRCTARVILSGTPVQNNAEELYRLIGWINSDVHSVLPPRVFTDLAGTINRYI------------------- A4HVU6/512-757 ---LNTEVRNTTVNINGADSSLPPLFVPTRLASHLAPVQLAALGFIVERTEKQSGCVVAMTMGLGKTLVALTLCFSQLHLAPQADILILTPKPIISHWVDEKNKWGMHGLHFPHFVASDGLNSLEFEQQLLEYERQRNNEKPKLGHIFVINGEYLAGFLRRFKRFTPLLMIVDEGHRVAAKGNKLTESLDRLRCNLRIVLSGTPLQNDASELYRLVGWVNKGVSRVLPPKRFQELANDINQFVEGDDGA------------- E9BBN9/436-681 ---LNTEVRNTTVNINGADSSLPPLFVPTRLASHLAPVQLAALGFIVERTEKQSGCVVAMTMGLGKTLVALTLCFSQLHLAPQADILILTPKPIISHWVDEKNKWGMHGLHFPHFVASDGLNSLEFEQQLLEYERQRNNEKPKLGHIFVINGEYLAGFLRRFKRFTPLLMIVDEGHRVAAKGNKLTESLDRLRCNLRIVLSGTPLQNDASELYRLVGWVNKGVSRVLPPKRFQELANDINQFVEGDDGA------------- A0A1E1IRJ8/511-759 --LLNTEIRHTTVNINEVDSSLPPLFVPTRLASQLAPVQLAALGFIVERTNKQSGCVVAMTMGLGKTLVALTLCFSHLHLAPQADILILTPKPIISHWVDEKNKWGMYGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKAGHVFVINSEYLAGFLRRFRRFTPFLIIVDEGHRVAAKGNKLTESLDRLRCNLRVVLSGTPLQNDASELYRLVGWVNKGVSKVLPPKRFQELANSINQFVEGDDGAF--------Y--- A0A088RKQ1/511-759 --LLNTEIRHTTVNINEVDSSLPPLFVPTRLASQLAPVQLAALGFIVERTNKQSGCVVAMTMGLGKTLVALTLCFSHLHLAPQADILILTPKPIISHWVDEKNKWGMYGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKAGHVFVINSEYLAGFLRRFRRFTPFLIIVDEGHRVAAKGNKLTESLDRLRCNLRVVLSGTPLQNDASELYRLVGWVNKGVSKVLPPKRFQELANSINQFVEGDDGAF--------Y--- E9APJ8/436-681 ---LNTEVRHTTVNINGADSSLPPLFVPTRLASHLAPVQLSALGFIVERAEKQSGCVVAMTMGLGKTLVALTLCFSQLHLAPQADILILTPKPIISHWVDEKNKWGMHGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKLGHIFVINGEYLAGFLRRFKRFTPLLMIVDEGHRVAAKGNKLTESLDRLRCNLRIVLSGTPLQNDASELYRLVGWVNKGVSRVLPPKRFQELANDINQFVEGDDGA------------- A0A061J8N3/488-746 KRDLLEKMRQTVVNLNAMDPNLPPIHVPGKLVGVLSPVQQAALGFVVDRLCKGNGCVIALTMGLGKTLLSLALCYSHLCDPNPRDVLILAPKLVLTHWLSEKQKWEKYGLVFAEFVVSDGTDSASFELSLKRYEQQINGEAPRTSHVFVINPEYIRSVMKKLTGFRPSLMIVDEGHRVSSKGGKLKDWLESMRCTARVILSGTPVQNNAEELYRLIGWTNNDVHSVLPPRVFTELAATINRYINGDDCAFSAAVSAQRY--- K2M079/487-738 -QRLLDKSRQSVMNLNTTDPNLPPIYLPGRLLEVLSPVQQAALGFVVDRLSKGNGCVIALTMGLGKTLLSLALCYSHLYDQSPRDILILAPKIVLTHWTGEKQKWENYGLIFPHFVVSDGTDSVSFEIALKRYKQQLNGELPRTSHVFVINPEYIRTVLKKLTGFRPSLIIVDEGHRVSSKGSKLKDWLEGLRCTARVILSGTPVQNNAEELYRLIGWINSDVHSVLPPRVFTELAGTINRYINGDDSAFTAA--------- Q4DUV6/389-629 --RLLDRSRQSVINLNATDPNLPPIYLPGRLLEVLSPVQQAALGFVVDRLSKGNGCVIALTMGLGKTLLSLALCYSHMYDQNPRDVLILAPKIVLTHWTGEKQKWEKYGLVFSHFVVSDGTDSVSFEIALKRYKQQLNGELPRTSHVFVINPEYIRTVLKKLTGFRPSLIIVDEGHRVSSKGSKLKDWLEGLRCTARVILSGTPVQNNAEELYRLIGWINSDVHSVLPPRVFTDLAGTINRYI------------------- V5BHQ6/489-729 --RLLDRSRQSVINLNATDPNLPPIYLPGRLLEVLSPAQQAALGFVVDRISKGNGCVIALTMGLGKTLLSLALCYSHMYDQNPRDVLILAPKIVLTHWAGEKQKWEKYGLVFSHFVVSDGTDSVSFEIALKRYKQQLNGELPRASHVFVINPEYIRTVLKKLTGFRPSLIIVDEGHRVSSKGSKLKDWLEGLRCTARVILSGTPVQNSAEELYRLIGWINNDVHSVLPPRVFTDLAGTINRYI------------------- #=GC scorecons 0014223244657969546549996569477543966694899697659436559996969999999966967979666344549799769946649944965994379949659766764694599349349669364639736779999569645685755595938779999967669659947397486955977969996996959999979967449556996739477654996773555242001000001000 #=GC scorecons_70 ____________****__*__****__*_**___*_*_*_*******_*__*__***_***********_******__*_____********__*_**__**_**__***_**_**__**_**__**__*__****_*_*_**__******_***___*_*___*_*_**********__**_**_*_**_*_*__***********_*_**********__*__*****_*_***__*****___________________ #=GC scorecons_80 ____________**_*_____***___*_*____*___*_***_*___*_____***_*_********__*__***________****__**____**__*__**__***_*__**______*__**__*__*__*_____**__******__*____*_*___*_*_*_******_*__*__**_*_**_*_*__****_***_**_*_********____*___**___*_*____**_**___________________ #=GC scorecons_90 _____________*_*_____***___*______*___*_***_*___*_____***_*_********__*__*_*________*_**__**____**__*__**___**_*__*_______*__**__*__*__*_____*_____****__*____*_____*_*_*__*****____*__**___*__*_*__*__*_***_**_*_*****_**____*___**___*______**______________________ //