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CATH Superfamily 3.30.70.100

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1666: Monooxygenase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Transferred entry: 1.14.14.18. [EC: 1.14.99.3]
    		10 A0A063XHY9 A0A0K6K9U2 A0A0K6LCP8 A0A0T8PYA3 A0A125UF48 A0A1D8FUR6 G4EZ33 L8AB58 O31534 U1Z682
    Heme oxygenase (biliverdin-producing). [EC: 1.14.14.18]
    Protoheme + 3 [reduced NADPH--hemoprotein reductase] + 3 O(2) = biliverdin + Fe(2+) + CO + 3 [oxidized NADPH--hemoprotein reductase] + 3 H(2)O.
    • This mammalian enzyme participates in the degradation of heme.
    • The terminal oxygen atoms that are incorporated into the carbonyl groups of pyrrole rings A and B of biliverdin are derived from two separate oxygen molecules.
    • The third oxygen molecule provides the oxygen atom that converts the alpha-carbon to CO.
    • The enzyme requires NAD(P)H and EC 1.6.2.4.
    • Cf. EC 1.14.15.20.
    • Formerly EC 1.14.99.3.
    		 7 A0A063XHY9 A0A0T8PYA3 A0A125UF48 A0A1D8FUR6 L8AB58 O31534 U1Z682
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