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CATH Superfamily 3.30.559.10

Chloramphenicol acetyltransferase-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Chloramphenicol acetyltransferase-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22346: BAHD family acyltransferase, clade V

There are 15 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Shikimate O-hydroxycinnamoyltransferase. [EC: 2.3.1.133]
4-coumaroyl-CoA + shikimate = CoA + 4-coumaroylshikimate.
  • Caffeoyl-CoA, feruloyl-CoA and sinapoyl-CoA can also act as donors, more slowly.
 38 A0A0B2P424 A0A0B2P5F0 A0A0B2P948 A0A0B2PA89 A0A0B2PGF1 A0A0B2Q2K7 A0A0B2Q6H6 A0A0B2Q7J0 A0A0B2QA62 A0A0B2QBQ7
(28 more...)
Anthranilate N-benzoyltransferase. [EC: 2.3.1.144]
Benzoyl-CoA + anthranilate = CoA + N-benzoylanthranilate.
  • Cinnamoyl-CoA, 4-coumaroyl-CoA and salicyloyl-CoA can act as donors, more slowly.
  • Involved in the biosynthesis of phytoalexins.
 16 A0A0B2Q2K7 A0A0B2Q6H6 A0A0B2Q7J0 A0A0B2R2K3 A0A0B2RDA1 B9RAB0 B9RGN0 B9RH39 B9RIV2 B9S6C4
(6 more...)
Quinate O-hydroxycinnamoyltransferase. [EC: 2.3.1.99]
Feruloyl-CoA + quinate = CoA + O-feruloylquinate.
  • Caffeoyl-CoA and 4-coumaroyl-CoA can also act as donors, more slowly.
  • Involved in the biosynthesis of chlorogenic acid in sweet potato and, with EC 2.3.1.98 in the formation of caffeoyl-CoA in tomato.
 6 A0A126Q9A5 A0A193BL31 A0A193BL33 A0A193BL34 H9N9G5 J7FPR4
10-deacetylbaccatin III 10-O-acetyltransferase. [EC: 2.3.1.167]
Acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III.
  • The enzyme will not acylate the hydroxy group at 1-beta, 7-beta, 13-alpha of 10-deacetylbaccatin III, or at 5-alpha of taxa-4(20), 11-dien-5-alpha-ol.
  • May be identical to EC 2.3.1.163.
 4 B9S966 D5K1Q6 Q6SQJ5 Q9M6E2
Taxadien-5-alpha-ol O-acetyltransferase. [EC: 2.3.1.162]
Acetyl-CoA + taxa-4(20),11-dien-5-alpha-ol = CoA + taxa-4(20),11-dien-5- alpha-yl acetate.
  • This is the third enzyme in the biosynthesis of the diterpenoid antineoplastic drug taxol (paclitaxel), which is widely used in the treatment of carcinomas, sarcomas and melanomas.
 4 B9SDE9 B9SDF5 Q8S9G6 Q9M6F0
Rosmarinate synthase. [EC: 2.3.1.140]
Caffeoyl-CoA + (R)-3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.
  • Involved with EC 1.1.1.237 in the biosynthesis of rosmarinic acid.
  • Characterized from the plant Melissa officinalis L. (lemon balm).
 4 A0A0A7RA06 A0PDV5 F2YNI5 G0LD36
Benzyl alcohol O-benzoyltransferase. [EC: 2.3.1.196]
Benzoyl-CoA + benzyl alcohol = CoA + benzyl benzoate.
  • The enzyme is involved in volatile benzenoid and benzoic acid biosynthesis.
  • The enzyme from Petunia hybrida also catalyzes the formation of 2-phenylethyl benzoate from benzoyl-CoA and 2-phenylethanol.
  • The apparent catalytic efficiency of the enzyme from Petunia hybrida with benzoyl-CoA is almost 6-fold higher than with acetyl-CoA.
 3 Q3ZPN4 Q8GT20 Q8GT21
Agmatine N(4)-coumaroyltransferase. [EC: 2.3.1.64]
4-coumaroyl-CoA + agmatine = CoA + N-(4-guanidinobutyl)-4- hydroxycinnamamide.
    		 2 A9ZPJ6 A9ZPJ7
    Tyramine N-feruloyltransferase. [EC: 2.3.1.110]
    Feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.
    • Cinnamoyl-CoA, 4-coumaroyl-CoA and sinapoyl-CoA can also act as donors.
    • Some aromatic amines can act as acceptors.
    		 2 D5FPG8 D5HQM4
    Omega-hydroxypalmitate O-feruloyl transferase. [EC: 2.3.1.188]
    Feruloyl-CoA + 16-hydroxypalmitate = CoA + 16-feruloyloxypalmitate.
    • p-coumaroyl-CoA and sinapoyl-CoA also act as substrates.
    • The enzyme is widely distributed in roots of higher plants.
    		 2 A0A178UGL4 Q94CD1
    2-alpha-hydroxytaxane 2-O-benzoyltransferase. [EC: 2.3.1.166]
    Benzoyl-CoA + 10-deacetyl-2-debenzoylbaccatin III = CoA + 10-deacetylbaccatin III.
    • The enzyme was studied using the semisynthetic substrate 2-debenzoyl- 7,13-diacetylbaccatin III.
    • It will not acylate the hydroxy group at 1-beta, 7-beta, 10-beta or 13-alpha of 10-deacetylbaccatin III, or at 2-alpha or 5-alpha of taxa-4(20),11-diene-2-alpha,5-alpha-diol.
    		 2 Q1X7Q0 Q9FPW3
    13-hydroxylupanine O-tigloyltransferase. [EC: 2.3.1.93]
    (E)-2-methylcrotonoyl-CoA + 13-hydroxylupanine = CoA + 13-((E)-2- methylcrotonoyl)oxylupanine.
    • Benzoyl-CoA and, more slowly, pentanoyl-CoA, 3-methylbutanoyl-CoA and butanoyl-CoA can act as acyl donors.
    • Involved in the synthesis of lupanine alkaloids.
    		 1 Q5H873
    (Z)-3-hexen-1-ol acetyltransferase. [EC: 2.3.1.195]
    Acetyl-CoA + (3Z)-hex-3-en-ol = (3Z)-hex-3-en-1-yl acetate + CoA.
    • The enzyme is resonsible for the production of (3Z)-hex-3-en-1-yl acetate, the major volatile compound released upon mechanical wounding of the leaves of Arabidopsis thaliana.
    		 1 Q9SRQ2
    Methanol O-anthraniloyltransferase. [EC: 2.3.1.232]
    Anthraniloyl-CoA + methanol = CoA + O-methyl anthranilate.
    • The enzyme from Concord grape (Vitis labrusca) is solely responsible for the production of O-methyl anthranilate, an important aroma and flavor compound in the grape.
    • The enzyme has a broad substrate specificity, and can use a range of alcohols with substantial activity, the best being butanol, benzyl alcohol, iso-pentanol, octanol and 2-propanol.
    • It can use benzoyl-CoA and acetyl-CoA as acyl donors with lower efficiency.
    • In addition to O-methyl anthranilate, the enzyme might be responsible for the production of ethyl butanoate, methyl-3-hydroxy butanoate and ethyl-3-hydroxy butanoate, which are present in large quantities in the grapes.
    • Also catalyzes EC 2.3.1.196.
    		 1 Q3ZPN4
    Spermidine disinapoyl transferase. [EC: 2.3.1.248]
    2 sinapoyl-CoA + spermidine = 2 CoA + N(1),N(8)-bis(sinapoyl)-spermidine.
    • The enzyme from the plant Arabidopsis thaliana has no activity with 4-coumaroyl-CoA (cf. EC 2.3.1.249).
    		 1 O80467
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