The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: NAC domain

The NAC protein family comprises a variety of plant proteins that are characterised by the presence of a highly conserved N-terminal NAC domain followed by diverse C-terminal domains. Structural domains comprising this superfamily share the structure of the NAC domain, an acronym derived from the names of the three genes first described as containing the domain, namely NAM (no apical meristem), ATAF1,2 and CUC2 (cup-shaped cotyledon). NAC proteins are involved in transcriptional regulation in several plant processes have been implicated in transcriptional control in a variety of plant processes in addition to being involved in responses to stress and viral infections. The NAC domain is responsible for DNA binding whilst the C-terminal regions constitute transcriptional activation domains PMID:15083810.

GO Diversity

Unique GO annotations
151 Unique GO terms

EC Diversity

Unique EC annotations
2 Unique EC terms

Species Diversity

Unique species annotations
269 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 7
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 1
Unique PDBs: 4
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Unique EC: 2
Unique GO: 151
Unique Species: 269