# STOCKHOLM 1.0
#=GF ID 3.20.20.70/FF/120108
#=GF DE tRNA-dihydrouridine(20) synthase [NAD(P)+]
#=GF AC 3.20.20.70/FF/120108
#=GF TP FunFam
#=GF DR CATH: 4.2
#=GF DR DOPS: 49.004
#=GS P53720/3-269      AC P53720
#=GS P53720/3-269      OS Saccharomyces cerevisiae S288C
#=GS P53720/3-269      DE tRNA-dihydrouridine(20) synthase [NAD(P)+]
#=GS P53720/3-269      DR GENE3D; b00cdeb0bf67ea9609b763adfa22f8dd/3-269; 
#=GS P53720/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS P53720/3-269      DR GO; GO:0005737; GO:0006400; GO:0008033; GO:0017150; 
#=GS P53720/3-269      DR EC; 1.3.1.91; 
#=GS O74731/5-265      AC O74731
#=GS O74731/5-265      OS Schizosaccharomyces pombe 972h-
#=GS O74731/5-265      DE tRNA-dihydrouridine(20) synthase [NAD(P)+]
#=GS O74731/5-265      DR GENE3D; ecfed761bec1536f4cda5a45b11707fd/5-265; 
#=GS O74731/5-265      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces; Schizosaccharomyces pombe; 
#=GS O74731/5-265      DR GO; GO:0005634; GO:0005737; GO:0006400; GO:0017150; 
#=GS O74731/5-265      DR EC; 1.3.1.91; 
#=GS A6ZS89/3-269      AC A6ZS89
#=GS A6ZS89/3-269      OS Saccharomyces cerevisiae YJM789
#=GS A6ZS89/3-269      DE tRNA-dihydrouridine synthase
#=GS A6ZS89/3-269      DR GENE3D; b00cdeb0bf67ea9609b763adfa22f8dd/3-269; 
#=GS A6ZS89/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS A6ZS89/3-269      DR EC; 1.3.1.91; 
#=GS N1NWS7/3-269      AC N1NWS7
#=GS N1NWS7/3-269      OS Saccharomyces cerevisiae CEN.PK113-7D
#=GS N1NWS7/3-269      DE tRNA-dihydrouridine synthase
#=GS N1NWS7/3-269      DR GENE3D; b00cdeb0bf67ea9609b763adfa22f8dd/3-269; 
#=GS N1NWS7/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS N1NWS7/3-269      DR EC; 1.3.1.91; 
#=GS B5VR46/3-269      AC B5VR46
#=GS B5VR46/3-269      OS Saccharomyces cerevisiae AWRI1631
#=GS B5VR46/3-269      DE tRNA-dihydrouridine synthase
#=GS B5VR46/3-269      DR GENE3D; b00cdeb0bf67ea9609b763adfa22f8dd/3-269; 
#=GS B5VR46/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS B5VR46/3-269      DR EC; 1.3.1.91; 
#=GS G2WL72/3-269      AC G2WL72
#=GS G2WL72/3-269      OS Saccharomyces cerevisiae Kyokai no. 7
#=GS G2WL72/3-269      DE tRNA-dihydrouridine synthase
#=GS G2WL72/3-269      DR GENE3D; b00cdeb0bf67ea9609b763adfa22f8dd/3-269; 
#=GS G2WL72/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS G2WL72/3-269      DR EC; 1.3.1.91; 
#=GS B3LPM7/3-269      AC B3LPM7
#=GS B3LPM7/3-269      OS Saccharomyces cerevisiae RM11-1a
#=GS B3LPM7/3-269      DE tRNA-dihydrouridine synthase
#=GS B3LPM7/3-269      DR GENE3D; b00cdeb0bf67ea9609b763adfa22f8dd/3-269; 
#=GS B3LPM7/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS B3LPM7/3-269      DR EC; 1.3.1.91; 
#=GS A0A0L8VJR3/3-269  AC A0A0L8VJR3
#=GS A0A0L8VJR3/3-269  OS Saccharomyces sp. 'boulardii'
#=GS A0A0L8VJR3/3-269  DE tRNA-dihydrouridine synthase
#=GS A0A0L8VJR3/3-269  DR GENE3D; b00cdeb0bf67ea9609b763adfa22f8dd/3-269; 
#=GS A0A0L8VJR3/3-269  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces sp. 'boulardii'; 
#=GS A0A0L8VJR3/3-269  DR EC; 1.3.1.91; 
#=GS A0A0L8RCL0/3-269  AC A0A0L8RCL0
#=GS A0A0L8RCL0/3-269  OS Saccharomyces eubayanus
#=GS A0A0L8RCL0/3-269  DE tRNA-dihydrouridine synthase
#=GS A0A0L8RCL0/3-269  DR GENE3D; 076f5188b54c754ee8e0fe5447cd84d4/3-269; 
#=GS A0A0L8RCL0/3-269  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces eubayanus; 
#=GS A0A1E5W8H3/1-246  AC A0A1E5W8H3
#=GS A0A1E5W8H3/1-246  OS Dichanthelium oligosanthes
#=GS A0A1E5W8H3/1-246  DE Uncharacterized protein
#=GS A0A1E5W8H3/1-246  DR GENE3D; 1a1b049506f643b3be207039066306c1/1-246; 
#=GS A0A1E5W8H3/1-246  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Paniceae; Dichantheliinae; Dichanthelium; Dichanthelium oligosanthes; 
#=GS C8ZFP2/3-269      AC C8ZFP2
#=GS C8ZFP2/3-269      OS Saccharomyces cerevisiae EC1118
#=GS C8ZFP2/3-269      DE tRNA-dihydrouridine synthase
#=GS C8ZFP2/3-269      DR GENE3D; 2a45be20235adf7f4db59bcc4ef82379/3-269; 
#=GS C8ZFP2/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS H0GMT6/1-257      AC H0GMT6
#=GS H0GMT6/1-257      OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7
#=GS H0GMT6/1-257      DE tRNA-dihydrouridine synthase
#=GS H0GMT6/1-257      DR GENE3D; 2c890d6de8a78f555281d54c75b99e42/1-257; 
#=GS H0GMT6/1-257      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; 
#=GS E7KHI6/1-257      AC E7KHI6
#=GS E7KHI6/1-257      OS Saccharomyces cerevisiae AWRI796
#=GS E7KHI6/1-257      DE tRNA-dihydrouridine synthase
#=GS E7KHI6/1-257      DR GENE3D; 45b0082fd317c0a3b771acb8cdda59cd/1-257; 
#=GS E7KHI6/1-257      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS H0H0H6/3-269      AC H0H0H6
#=GS H0H0H6/3-269      OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7
#=GS H0H0H6/3-269      DE tRNA-dihydrouridine synthase
#=GS H0H0H6/3-269      DR GENE3D; 4ebded1c94982024e75ce16effa30822/3-269; 
#=GS H0H0H6/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae x Saccharomyces kudriavzevii; 
#=GS C7GLP0/3-269      AC C7GLP0
#=GS C7GLP0/3-269      OS Saccharomyces cerevisiae JAY291
#=GS C7GLP0/3-269      DE tRNA-dihydrouridine synthase
#=GS C7GLP0/3-269      DR GENE3D; 6c54ea7bd7cac294b0a80b3c88a00586/3-269; 
#=GS C7GLP0/3-269      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GS E7LZR1/1-246      AC E7LZR1
#=GS E7LZR1/1-246      OS Saccharomyces cerevisiae Vin13
#=GS E7LZR1/1-246      DE tRNA-dihydrouridine synthase
#=GS E7LZR1/1-246      DR GENE3D; 710c964a8d1b0e2998f51ea3991a2b2b/1-246; 
#=GS E7LZR1/1-246      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae; 
#=GF TC 447.8 4.8E-138
#=GF SQ 16
P53720/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
O74731/5-265              NYSNKVCLAPMVRIGELPMRLLALRYGANLVWGPEIVDKALLSGTPVERVVNDRINCIDFVKPPS-----NKVLFRVHP-LEANRLIFQLGSASPELAVEAAKLVANDVAGIDLNCGCPKHFSVHAGMGAGLLKNQDRLVSILDALVNEIGKPYKISISCKIRLLETKEDTLKLVERICDTGVRAITVHCRTTPMRNTEPADRSYLSEIVGVCRNKDVSILVNGDVLSYNDGLDVIEKYGVD---GVLIARAAERNVSCFRIEGPLSSFK
A6ZS89/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
N1NWS7/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
B5VR46/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
G2WL72/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
B3LPM7/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
A0A0L8VJR3/3-269          TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
A0A0L8RCL0/3-269          TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLVQCV---RRENTTLQTVDYVVPSKVQARPETLVFRTYPKLESSKLIFQLGSASPALATQAALKVIGDVNGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGKPHGKPISVKIRLLDTEQDTLQLVTCLCATGISNLTVHCRKTEMRNREQPITDYIAAIYGICQSNNVSLIVNGAIRDRAHFHELQSNHWNNTKIGGMIAECAERNPAVFDHPTSETKDV
A0A1E5W8H3/1-246          ---------------------MALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
C8ZFP2/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCI---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLNTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
H0GMT6/1-257              ----------MVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCI---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
E7KHI6/1-257              ----------MVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLIKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
H0H0H6/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIVDKKLLQCT---RRENTTLQTVDYVVPSKAQARPETLVFRTYPKLESSRLIFQIGSASPALAIQAALKVINDVNGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILQELVKNVGKPHGKPISVKIRLLDTEQDTLQLVTRLCATGIANLTVHCRKTEMRNREQPITDYIAEIYEVCRANNVSLIVNGAIHDRSHFHDLQTNHWGNSSIGGMIAECAERNPTVFDHTAHVPEQV
C7GLP0/3-269              TYAGKLVLAPMVRAGELPTRLMALAHGADLVWSPEIIDKKLIQCI---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLDTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
E7LZR1/1-246              ---------------------MALAHGADLVWSPEIIDKKLIQCV---RKENTALQTVDYVVPSKVQTRPETLVFRTYPKLESSKLIFQIGSASPALATQAALKVINDVSGIDINAGCPKHFSIHSGMGSALLRTPDTLCLILKELVKNVGNPHSKPISVKIRLLNTKQDTLQLVKRLCATGITNLTVHCRKTEMRNREQPITDYIAEIYEICQANNVSLIVNGAIRDRSHFHDLQANHWKNTNIGGMIAECAERDPTVFDHTSKPSEDG
#=GC scorecons            343243244466646666466799679969996999799696665000945965666797959664444466669967949966799996999996995699559689959996969999999796999669976696955995699667969745699599999697699969857696997466999996959996966566966795679656699669996756556458654675464349579966999666596555447544
#=GC scorecons_70         __________***_****_*****_**************_*_______*__*__**_****_**______*_*******_***************_**_***__*****_*****_*********************_*__**__******_**__***_***************_***_***_*******_*_***_***__******__***_*********_*_*__*__**__**__*___*_****_****___*______*___
#=GC scorecons_80         ______________________**_***_***_***_**_*_______*__*_____****_*___________**_**_**___****_*****_**__**__*_***_***_*_*********_***__***__*_*__**__**__**_**___**_*****_**_***_**_*_*_***___*****_*_***_*_____*__**___*____**__***_*_______*____*______*__**__***____*______*___
#=GC scorecons_90         ______________________**__**_***_***_**_*_______*__*______*_*_*___________**__*_**___****_*****_**__**__*__**_***_*_*******_*_***__**___*_*__**__**___*_*____**_*****_*__***_**___*_**____*****_*_***_*_____*___*___*____**__***_________*___________*__**__***____*__________
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