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CATH Superfamily 3.10.20.30

Beta-grasp domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22439: Succinate dehydrogenase iron-sulfur subunit

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Succinate dehydrogenase (quinone). [EC: 1.3.5.1]
Succinate + a quinone = fumarate + a quinol.
  • The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of many aerobic or facultative bacteria.
  • It catalyzes succinate oxidation in the citric acid cycle and transfers the electrons to quinones in the membrane, thus constituting a part of the aerobic respiratory chain (known as complex II).
  • In vivo the enzyme uses the quinone found in the organism - eukaryotic enzymes utilize ubiquinone, bacterial enzymes utilize ubiquinone or menaquinone, and archaebacterial enzymes from the Sulfolobus genus use caldariellaquinone.
  • Cf. EC 1.3.5.4.
 5345 A0A010P684 A0A010S5A8 A0A011MFT2 A0A011TF78 A0A011TIK1 A0A011V117 A0A013WQT8 A0A014N290 A0A014P725 A0A014Q658
(5335 more...)
Deleted entry. [EC: 1.3.99.1]
    		446 A0A009GHD5 A0A009IVG1 A0A009K3B5 A0A009QCF3 A0A009RJM7 A0A011N954 A0A011PCU8 A0A011Q665 A0A023CAB7 A0A023WT20
    (436 more...)
    Fumarate reductase (quinol). [EC: 1.3.5.4]
    Succinate + a quinone = fumarate + a quinol.
    • The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain.
    • The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, to which it is closely related.
    		 3 A0A081N7D3 A0A142BAM7 A0A1L8CNT4
    Acid phosphatase. [EC: 3.1.3.2]
    A phosphate monoester + H(2)O = an alcohol + phosphate.
    • Wide specificity.
    • Also catalyzes transphosphorylations.
    		 1 A0A0P1AG99