The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Neurotransmitter-gated ion-channel ligand-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
2370
6590
3D
5afhA00 - 80.7
2365
2454 - - 81.8
2378
1942
EC
3D
4cofA01 - 79.9
2358
1234
3D
5cfbA01 - 86.9
2394
Serotonin
468
3D
4pirA01 - 86.5
2310
464 - - 72.2
2363
281
3D
4tnvA01 - 87.2
2343
232 - - 72.4
2409
211
3D
2yksA01 - 64.3
2327
167
3D
2qc1B00 - 67.4
870
131 - - 37.2
2266
84 - - 34.7
2122
36 - - 24.9
2379
30 - - 69.9
2357
24 - - 60.3
52
19 - - 23.1
1099
12 - - 37.9
37
8 - - 28.6
561
8 - - 5.4
2322
7 - - 20.3
89
6 - - 11.5
1156
6 - - 9.9
100
5 - - 16.0
728
4 - - 10.6
1139
4 - - 12.0
1087
4 - - 15.9
2263
4 - - 12.8
790
3 - - 7.6
636
3 - - 22.9
2235
3 - - 6.9
1127
Dbeta3
3 - - 6.7
2088
2 - - 0.0
75
2 - - 7.6
2314
2 - - 18.1
1988
1 - - 0.0
2242
1 - - 0.0
33
1 - - 0.0
1420
1 - - 0.0