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CATH Superfamily 2.60.120.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2773: Putative genome polyprotein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA-directed 5'-3' RNA polymerase activity GO:0003968
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
 2 P03300 (/IDA) P03304 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 1 P03304 (/IPI)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Suppression by virus of host mRNA export from nucleus GO:0039522
Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism.
 20 O41174 (/ISS) P03301 (/ISS) P03302 (/ISS) P03304 (/ISS) P04936 (/ISS) P06209 (/ISS) P06210 (/ISS) P07210 (/ISS) P12915 (/ISS) P12916 (/ISS)
(10 more)
Suppression by virus of host RIG-I activity by RIG-I proteolysis GO:0039544
The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction.
 18 O41174 (/ISS) P03301 (/ISS) P03302 (/ISS) P03304 (/ISS) P04936 (/ISS) P06209 (/ISS) P06210 (/ISS) P07210 (/ISS) P12915 (/ISS) P12916 (/ISS)
(8 more)
Suppression by virus of host translation initiation factor activity GO:0039611
Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor.
 18 O41174 (/ISS) P03301 (/ISS) P03302 (/ISS) P06209 (/ISS) P06210 (/ISS) P07210 (/ISS) P12915 (/ISS) P12916 (/ISS) P22055 (/ISS) P23008 (/ISS)
(8 more)
Positive stranded viral RNA replication GO:0039690
A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.
 18 O41174 (/ISS) P03301 (/ISS) P03302 (/ISS) P04936 (/ISS) P06209 (/ISS) P06210 (/ISS) P07210 (/ISS) P12915 (/ISS) P12916 (/ISS) P22055 (/ISS)
(8 more)
Induction by virus of host autophagy GO:0039520
Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.
 17 O41174 (/ISS) P03301 (/ISS) P03302 (/ISS) P03304 (/ISS) P06209 (/ISS) P06210 (/ISS) P07210 (/ISS) P12915 (/ISS) P22055 (/ISS) P23069 (/ISS)
(7 more)
Suppression by virus of host RIG-I activity by RIG-I proteolysis GO:0039544
The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction.
 3 P03300 (/IDA) P23008 (/IDA) Q82122 (/IDA)
Induction by virus of host autophagy GO:0039520
Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.
 2 P03300 (/IDA) P04936 (/IDA)
Suppression by virus of host translation initiation factor activity GO:0039611
Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor.
 2 P03300 (/IDA) P04936 (/IDA)
Positive stranded viral RNA replication GO:0039690
A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.
 2 P03300 (/IDA) Q82122 (/IDA)
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
 1 B2ZUN1 (/IDA)
Suppression by virus of host mRNA export from nucleus GO:0039522
Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism.
 1 P03300 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Viral capsid GO:0019028
The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.
 1 Q66776 (/IDA)