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CATH Superfamily 2.60.120.180

Glycoside hydrolase family 11/12, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Glycoside hydrolase family 11/12, catalytic domain

Glycoside hydrolases are ubiquitous enzymes involved in biochemical degradation of cellulose and hemicellulose, the main constituents of plant cell walls PMID:15853815. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families PMID:7624375,PMID:8535779. Glycoside hydrolase family 11 (GH11) comprises enzymes with only one known activity, xylanase, while family 12 (GH12) comprises enzymes with two known activities, endoglucanase and xyloglucan hydrolase.

PMID:15853815 PMID:7624375 PMID:8535779 (INTERPRO:IPR013319)

GO Diversity

Unique GO annotations
18 Unique GO terms

EC Diversity

Unique EC annotations
11 Unique EC terms

Species Diversity

Unique species annotations
1825 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 259
Domain clusters (>95% seq id): 41
Domain clusters (>35% seq id): 12
Unique PDBs: 147
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 3
Function
Unique EC: 11
Unique GO: 18
Taxonomy
Unique Species: 1825