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CATH Superfamily 2.10.25.10

Laminin

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11604: EPI-1, isoform e

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
 1 Q21313 (/ISS)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Reproduction GO:0000003
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Neuron migration GO:0001764
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Axonal defasciculation GO:0007414
Separation of axons away from a bundle of axons known as a fascicle.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Positive regulation of endopeptidase activity GO:0010950
Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Positive regulation of locomotion GO:0040017
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Regulation of cell proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Response to misfolded protein GO:0051788
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
 4 C1P640 (/IMP) C1P641 (/IMP) G5EEV6 (/IMP) Q21313 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Basement membrane GO:0005604
A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
 4 C1P640 (/IDA) C1P641 (/IDA) G5EEV6 (/IDA) Q21313 (/IDA)