View in Gene3D

CATH Superfamily 1.20.58.610

Cdc37, Hsp90 binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Cdc37, Hsp90 binding domain

This superfamily includes Cdc37, a molecular chaperone required for the activity of numerous eukaryotic protein kinases. This entry corresponds to the Hsp90 chaperone (heat shock protein 90) binding domain of Cdc37 PMID:16098195. It is found between the N-terminal Cdc37 domain INTERPRO:IPR013855, PFAM:PF03234, which is predominantly involved in kinase binding, and the C-terminal domain of Cdc37 INTERPRO:IPR013873, PFAM:PF08564 whose function is unclear.

INTERPRO:IPR013874, PFAM:PF08565

GO Diversity

Unique GO annotations
44 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
902 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 3
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO: 44
Taxonomy
Unique Species: 902