The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Rhopdopsin 7-helix transmembrane proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
45522
50267
EC
- - 93.6
45636
17672
EC
- - 91.1
45459
Serotonin
11439
EC
- - 92.4
45564
9770
EC
- - 95.5
45749
5848
EC
- - 83.9
45687
5294
EC
- - 86.3
45721
3756 - - 79.3
45452
3399
EC
- - 93.7
45700
3386 - - 80.0
45375
Cone pigments
3022
EC
- - 88.9
45689
2845
EC
- - 95.6
45381
2478 - - 93.7
45670
2163
EC
- - 93.4
45767
1949 - - 95.6
45598
1921
EC
- - 85.1
45266
1899 - - 83.7
45613
1690 - - 91.5
45416
Drosophila
1435 - - 87.9
45451
1404
EC
- - 94.6
45629
1337
EC
- - 88.1
3477
1298 - - 94.1
45696
1248 - - 93.4
45589
1202 - - 88.6
45655
1084 - - 89.8
45705
976 - - 98.0
45181
966 - - 88.3
45254
850 - - 96.4
7072
727 - - 94.6
45322
682
EC
- - 88.4
45807
579 - - 95.2
45778
536 - - 94.3
45672
501 - - 93.5
44876
478 - - 91.4
11965
457 - - 88.6
44887
375 - - 87.8
44476
364 - - 93.6
45560
Drosophila
355 - - 87.8
45369
349 - - 91.1
45736
331 - - 94.7
43876
304 - - 94.2
45362
295 - - 78.5
45065
287 - - 87.6
44921
280 - - 91.9
45745
255 - - 86.9
44824
250 - - 48.7
43882
243 - - 84.0
44943
231 - - 85.0
44878
213 - - 82.1
45134
211 - - 86.0
45763
206 - - 96.1
44339
204
EC
- - 75.2
43720
190 - - 71.1
44232
176 - - 75.6
45388
167 - - 89.1
43944
154 - - 88.7
45643
146 - - 80.1
44398
141 - - 71.8
45674
140 - - 92.0
44057
133 - - 89.0
44803
128 - - 88.5
43143
121 - - 52.9
3414
118 - - 64.0
45157
111 - - 82.0
44437
110 - - 73.8
45179
109 - - 75.7
45802
100 - - 88.3
43883
96 - - 74.9
44944
95 - - 54.8
45646
92 - - 91.9
44851
89 - - 63.4
44371
87 - - 46.6
3938
83 - - 76.3
23239
81 - - 71.1
4818
75 - - 61.9
43297
73 - - 70.7
45788
73 - - 90.5
45330
72 - - 76.7
31715
70 - - 20.7
43330
69 - - 71.1
44950
68 - - 47.4
7786
67 - - 54.6
44097
66 - - 67.0
43177
64 - - 78.4
45109
63
EC
- - 67.7
3998
60
EC
- - 78.2
43248
55 - - 76.2
45552
47 - - 59.3
44869
47 - - 69.0
44060
46 - - 48.5
44067
45 - - 61.7
44189
44 - - 57.0
44907
43 - - 69.5
43862
41 - - 45.8
12991
39 - - 43.0
45576
38 - - 54.1
4985
38 - - 44.0
43667
36 - - 43.4
30970
36 - - 90.9
43314
35 - - 30.4
9510
34 - - 15.4
44310
33 - - 52.9
43904
31 - - 29.9
23237
30 - - 50.6
44905
30 - - 61.9
44470
30 - - 41.2
5710
29 - - 55.1
22847
29 - - 26.5
44066
26 - - 27.4
676
26 - - 78.4
3176
25 - - 26.2
44325
24 - - 52.3
14589
24 - - 60.0
34983
22 - - 43.2
44258
22 - - 26.2
43368
21 - - 31.4
43798
21 - - 34.0
4101
21 - - 28.0
44308
20 - - 36.0
43964
19 - - 43.6
511
19 - - 16.8
44884
19 - - 43.3
6380
19 - - 19.4
5025
18 - - 19.2
43687
18 - - 37.7
45743
17 - - 26.5
2383
17 - - 25.1
45185
17 - - 39.6
43267
17 - - 22.4
2627
16 - - 15.6
43674
16 - - 47.6
43678
16 - - 15.9
2314
16 - - 80.0
3550
16 - - 52.8
43597
14 - - 21.8
44246
14 - - 9.1
5296
12 - - 49.5
212
12 - - 19.4
43792
12 - - 28.2
32745
11 - - 69.0
18866
11 - - 3.8
11136
11 - - 11.5
37846
U51
10 - - 14.8
3417
10 - - 14.4
32744
9 - - 0.0
17253
9 - - 38.4
31905
9 - - 0.0
599
9 - - 9.7
45799
8 - - 39.2
6649
8 - - 46.9
45785
8 - - 39.9
7408
8 - - 24.7
4681
7 - - 14.5
38070
7 - - 12.6
31331
7 - - 12.0
2166
7 - - 29.9
44247
Serotonin
7 - - 34.7
452
7 - - 10.9
44101
7 - - 5.3
9644
7 - - 9.0
22436
7 - - 11.8
31848
6 - - 2.6
31709
6 - - 20.8
1282
6 - - 8.5
42239
6 - - 8.5
30079
6 - - 3.1
388
6 - - 5.0
76
5 - - 4.9
401
5 - - 15.8
4887
5 - - 18.8
45726
5 - - 56.3
2815
5 - - 18.6
25118
5 - - 15.2
631
5 - - 17.3
17914
5 - - 4.9
33077
5 - - 9.4
14614
4 - - 6.2
1816
4 - - 17.0
6895
4 - - 25.1
25727
4 - - 5.1
31533
4 - - 6.2
43773
4 - - 10.3
1476
4 - - 2.1
9732
4 - - 20.2
45635
4 - - 40.3
27851
4 - - 0.0
31275
4 - - 11.5
25364
3 - - 13.3
5218
3 - - 15.0
3981
3 - - 10.3
45107
3 - - 0.0
45744
3 - - 36.8
43475
3 - - 4.7
44968
3 - -
45738
3 - - 59.5
4238
3 - - 5.9
25936
2 - - 8.3
311
2 - - 0.0
45491
2 - - 28.8
7700
2 - - 9.3
45797
2 - - 36.8
6401
2 - - 11.4
6610
2 - - 2.1
45801
2 - - 40.4
45377
2 - - 33.5
30891
2 - - 0.0
45476
2 - - 30.4
43613
2 - - 13.1
35221
2 - - 2.0
2162
2 - - 10.4
45805
2 - - 40.4
45811
2 - - 38.2
45161
2 - - 26.4
45625
2 - - 34.4
45720
2 - - 37.0
28019
1 - - 0.0
10830
1 - - 0.0
43278
1 - - 0.0
28576
1 - - 0.0
45575
1 - - 0.0
41886
1 - - 0.0
28013
1 - - 0.0
45808
1 - - 0.0
32186
1 - - 0.0
42967
1 - - 0.0
41846
1 - - 0.0
28941
1 - - 0.0
40215
1 - - 0.0
45717
1 - - 0.0
29303
AFU_orthologue AFUA_2G12640
1 - - 0.0
43507
1 - -
29022
1 - - 0.0
1938
1 - - 0.0
30244
1 - - 0.0
43139
1 - - 0.0
42312
1 - - 0.0
28014
1 - - 0.0
45651
1 - - 0.0